{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:44:42Z","timestamp":1786999482813,"version":"build-2736575974"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215123001226_sec_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Functional endoscopic sinus surgery for chronic rhinosinusitis improves sinus drainage and intranasal medication delivery. This study compares medication delivery with commonly used devices in normal and altered anatomy (post functional endoscopic sinus surgery) using sinus surgery models (Phacon).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215123001226_sec_a2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medication delivery was simulated via nasal drops, nasal spray and an irrigation device (Neilmed Sinus Rinse). Coverage was then calculated from endoscopic pictures taken at various anatomical sites in the normal nose and post functional endoscopic sinus surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215123001226_sec_a3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In the normal nose, nasal spray did not penetrate the sphenoid sinus, and drops bypassed the vestibule anteriorly. Neilmed Sinus Rinse provided superior coverage at the sphenoid site following sphenoidectomy and the frontal site following Draf III. After ethmoidectomy, nasal drops overall provided less coverage than the other methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215123001226_sec_a4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Neilmed Sinus Rinse generally provided the best distribution, followed by the nasal spray and then nasal drops. The type and extent of surgery also affects medication delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215123001226","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T05:55:11Z","timestamp":1689659711000},"page":"310-314","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of intranasal medication delivery devices before and after functional endoscopic sinus surgery using Phacon sinus surgery models"],"prefix":"10.1017","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5742-8740","authenticated-orcid":false,"given":"Christoforos","family":"Constantinou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Yap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arbaaz","family":"Pervaiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Bandino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeeva","family":"Jeyaretna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Martinez-Devesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Qureishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,7,18]]},"reference":[{"key":"S0022215123001226_ref5","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4602651"},{"key":"S0022215123001226_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.10.007"},{"key":"S0022215123001226_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00004"},{"key":"S0022215123001226_ref17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-66716-0"},{"key":"S0022215123001226_ref14","first-page":"257","article-title":"Quantification of airflow in the sinuses following functional endoscopic sinus surgery","volume":"58","author":"Siu","year":"2020","journal-title":"Rhinology"},{"key":"S0022215123001226_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.04.020"},{"key":"S0022215123001226_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004458.pub2"},{"key":"S0022215123001226_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/BF00183169"},{"key":"S0022215123001226_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2012.03.002"},{"key":"S0022215123001226_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21879"},{"key":"S0022215123001226_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70001-9"},{"key":"S0022215123001226_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215112000205"},{"key":"S0022215123001226_ref6","first-page":"102","article-title":"The \u2018best method\u2019 of topical nasal drug delivery: comparison of seven techniques","volume":"44","author":"Merkus","year":"2006","journal-title":"Rhinology"},{"key":"S0022215123001226_ref2","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22324"},{"key":"S0022215123001226_ref12","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino13.065"},{"key":"S0022215123001226_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2018.01.011"},{"key":"S0022215123001226_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.10.001"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215123001226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T04:40:38Z","timestamp":1708058438000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215123001226\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,18]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["S0022215123001226"],"URL":"https:\/\/doi.org\/10.1017\/s0022215123001226","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,18]]}}}