{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:54:36Z","timestamp":1761710076008,"version":"3.40.5"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T00:00:00Z","timestamp":1700179200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215123002001_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>To evaluate if fusion computed tomography\u2013diffusion-weighted magnetic resonance imaging may have a role in the pre-operative assessment of congenital middle-ear cholesteatoma.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215123002001_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A retrospective chart review of surgically treated congenital middle-ear cholesteatoma patients over a 2-year timespan was conducted. Pre-operative staging was performed on computed tomography and fusion computed tomography\u2013diffusion-weighted magnetic resonance imaging based on extension of the disease according to the ChOLE classification system and the Potsic classification system. Intra-operative staging was compared to imaging findings to evaluate accuracy of the two imaging modalities in predicting congenital middle-ear cholesteatoma extent.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215123002001_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Computed tomography was able to correctly predict congenital middle-ear cholesteatoma extent in three out of six cases according to the ChOLE classification system, all of which were staged as Ch1a and Ch1b on pre-operative computed tomography. Cases in which computed tomography was not able correctly to determine congenital middle-ear cholesteatoma extent were staged as Ch3 on pre-operative computed tomography. Fusion scans correctly determined congenital middle-ear cholesteatoma extent in all cases according to the ChOLE classification.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215123002001_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Fusion computed tomography\u2013diffusion-weighted magnetic resonance imaging may be helpful in cases of congenital middle-ear cholesteatoma where pre-operative computed tomography shows mastoid and antrum opacification, in which computed tomography alone may overestimate cholesteatoma extension beyond the level of the lateral semi-circular canal.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215123002001","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T02:54:56Z","timestamp":1700189696000},"page":"507-511","source":"Crossref","is-referenced-by-count":1,"title":["Fusion computed tomography\u2013magnetic resonance imaging scans for pre-operative staging of congenital middle-ear cholesteatoma"],"prefix":"10.1017","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0508-519X","authenticated-orcid":false,"given":"Francesco","family":"Maccarrone","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8484-4961","authenticated-orcid":false,"given":"Carla","family":"Cantaffa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurilio","family":"Genovese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sauro","family":"Tassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Negri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,11,17]]},"reference":[{"key":"S0022215123002001_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000007080"},{"key":"S0022215123002001_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2012.10.007"},{"key":"S0022215123002001_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000136875.41630.d6"},{"key":"S0022215123002001_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-021-01342-4"},{"key":"S0022215123002001_ref6","first-page":"847","article-title":"Diffusion-weighted imaging for differentiating recurrent cholesteatoma from granulation tissue after mastoidectomy: case report","volume":"23","author":"Maheshwari","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"S0022215123002001_ref3","doi-asserted-by":"publisher","DOI":"10.4274\/MMJ.galenos.2022.28928"},{"key":"S0022215123002001_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.109788"},{"key":"S0022215123002001_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002039"},{"key":"S0022215123002001_ref10","doi-asserted-by":"publisher","DOI":"10.1155\/DTE.7.99"},{"key":"S0022215123002001_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3467-7"},{"key":"S0022215123002001_ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.1663"},{"key":"S0022215123002001_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2020.09.014"},{"key":"S0022215123002001_ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12081349"},{"key":"S0022215123002001_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.05.017"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215123002001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T08:12:19Z","timestamp":1714551139000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215123002001\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,17]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0022215123002001"],"URL":"https:\/\/doi.org\/10.1017\/s0022215123002001","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2023,11,17]]}}}