{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T04:07:43Z","timestamp":1741666063519,"version":"3.38.0"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T00:00:00Z","timestamp":1735257600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S002221512400104X_sec_a1\"><jats:title>Objectives<\/jats:title><jats:p>This study aimed to explore the influence of laryngopharyngeal reflux on the features of vocal fold polyps and prognosis after office-based transnasal vocal fold polypectomy.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512400104X_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Eighty-four vocal fold polyp patients were retrospectively analysed. Patients were assigned to laryngopharyngeal reflux or non-laryngopharyngeal reflux groups using pre-operative Reflux Symptom Score-12.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512400104X_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>The laryngopharyngeal reflux group had significantly higher pre-operative Reflux Sign Assessment scores, worse lifestyle and worse eating habits than the non-laryngopharyngeal reflux group. After office-based transnasal vocal fold polypectomy, the Reflux Symptom Score-12 and Reflux Sign Assessment score decreased in both groups, although the laryngopharyngeal reflux group still had higher values. The non-laryngopharyngeal reflux group had better vocal fold morphology recovery than the laryngopharyngeal reflux group. Multivariate logistic regression analysis demonstrated that smoking and a higher pre-operative Reflux Symptom Score-12 score were independent risk factors for poor prognosis.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512400104X_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Laryngopharyngeal reflux is detrimental to vocal fold recovery of vocal fold polyp patients following office-based transnasal vocal fold polypectomy. For vocal fold polyp patients with laryngopharyngeal reflux, lifestyle and diet guidance should be focused.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s002221512400104x","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T03:36:35Z","timestamp":1735270595000},"page":"54-59","source":"Crossref","is-referenced-by-count":0,"title":["Laryngopharyngeal reflux leads to adverse short-term outcomes of vocal fold polyp patients after office-based transnasal vocal fold polypectomy"],"prefix":"10.1017","volume":"139","author":[{"given":"Jing","family":"He","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianwen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renchuan","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1583-0983","authenticated-orcid":false,"given":"Yi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,12,27]]},"reference":[{"key":"S002221512400104X_ref2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819827488"},{"key":"S002221512400104X_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/0145561319838725"},{"key":"S002221512400104X_ref1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24911"},{"key":"S002221512400104X_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2017.09.004"},{"key":"S002221512400104X_ref17","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.414"},{"key":"S002221512400104X_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(02)00097-8"},{"key":"S002221512400104X_ref10","doi-asserted-by":"publisher","DOI":"10.1177\/0003489419888947"},{"key":"S002221512400104X_ref3","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816676471"},{"key":"S002221512400104X_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2022.02.025"},{"key":"S002221512400104X_ref6","first-page":"51","article-title":"Prognosis of laryngeal polyp surgery combined with anti-acid treatment on laryngopharyngeal reflux in association with vocal cord polyp","volume":"26","author":"Bai","year":"2018","journal-title":"Chin J Otorhinolaryngol Integ Med"},{"key":"S002221512400104X_ref13","first-page":"1087","article-title":"Analysis of reliability and validity of the Chinese version of reflux symptom score 12 [in Chinese]","volume":"57","author":"Zheng","year":"2022","journal-title":"Zhonghua er bi yan hou tou Jing wai ke za zhi [Chin J Otorhinolaryngol Head Neck Surg]"},{"key":"S002221512400104X_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0744-3"},{"key":"S002221512400104X_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05711-2"},{"key":"S002221512400104X_ref15","first-page":"540","article-title":"Clinical analysis of patients with laryngopharyngeal reflux disease","volume":"24","author":"Cheng","year":"2017","journal-title":"Chin Arch Otolaryngol Head Neck Surg"},{"key":"S002221512400104X_ref12","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28017"},{"key":"S002221512400104X_ref11","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820941003"},{"key":"S002221512400104X_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2017.07.007"},{"key":"S002221512400104X_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25088"},{"key":"S002221512400104X_ref4","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1055\/s-0038-1675391","article-title":"Vocal fold polyps: literature review","volume":"23","author":"de Vasconcelos","year":"2019","journal-title":"Int Arch Otorhinolaryngol"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221512400104X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T09:52:23Z","timestamp":1741600343000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221512400104X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,27]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S002221512400104X"],"URL":"https:\/\/doi.org\/10.1017\/s002221512400104x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2024,12,27]]}}}