{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T04:09:40Z","timestamp":1742875780610,"version":"3.40.2"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215124001270_sec_a1\"><jats:title>Objectives<\/jats:title><jats:p>To assess the value of corrected calcium decline at 6 hours as a predictor of hypocalcaemia post total thyroidectomy by comparing it to the currently widely used intact parathyroid hormone.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001270_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of patients who underwent total thyroidectomy from January 2016 to February 2020. Serum intact parathyroid hormone and corrected calcium data pre-operatively and 6 hours post-operatively were obtained. Receiver operating characteristic curves were used to compare corrected calcium decline at 6 hours versus 6 hours for relative intact parathyroid hormone decline as predictors of hypocalcaemia, and the area under the curve for each metric was reported.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001270_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Patients included in this analysis totalled 209. The receiver operating characteristic analysis suggested that corrected calcium decline at 6 hours has a similar predictive value to 6 hours relative intact parathyroid hormone. The areas under the curves for predicting hypocalcaemia were 0.797 for corrected calcium decline at 6 hours and 0.737 for 6 hours relative intact parathyroid hormone, but the difference (0.06) was not statistically significant.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001270_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that corrected calcium decline at 6 hours has a similar predictive value to 6 hours relative intact parathyroid hormone and hence has the potential to predict post-operative hypocalcaemia.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215124001270","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T08:35:19Z","timestamp":1729586119000},"page":"125-128","source":"Crossref","is-referenced-by-count":0,"title":["Serum calcium relative decline as a predictor of post thyroidectomy hypocalcaemia"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6150-2678","authenticated-orcid":false,"given":"Hamed","family":"Al Maawali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahya","family":"Al Badaai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,10,22]]},"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215124001270","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T15:16:17Z","timestamp":1742829377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215124001270\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,22]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0022215124001270"],"URL":"https:\/\/doi.org\/10.1017\/s0022215124001270","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2024,10,22]]}}}