{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T18:08:21Z","timestamp":1778695701229,"version":"3.51.4"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"funder":[{"DOI":"10.13039\/100031022","name":"Center for Cancer Research","doi-asserted-by":"publisher","award":["R25CA181003"],"award-info":[{"award-number":["R25CA181003"]}],"id":[{"id":"10.13039\/100031022","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,3]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n The adipofascial anterolateral thigh (AF-ALT) free flap represents a versatile technique in head and neck reconstructions, with its applications increasingly broadening. The objective was to detail the novel utilization of the AF-ALT flap in orbital and skull base reconstruction, along with salvage laryngectomy onlay in our case series.<\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n We conducted a retrospective analysis at Roswell Park Comprehensive Cancer Center, spanning from July 2019 to June 2023, focusing on patient demographics and reconstructive parameters data.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The AF-ALT flap was successfully employed in eight patients (average age 59, body mass index [BMI] 32.0) to repair various defects. Noteworthy outcomes were observed in skull base reconstructions, with no flap failures or major complications over an average 12-month follow-up. Donor sites typically healed well with minimal interventions.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Our series is the first to report the AF-ALT flap's efficacy in anterior skull base and orbital reconstructions, demonstrating an additional innovation in complex head and neck surgeries.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/s0022215124001385","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:25:50Z","timestamp":1729470350000},"page":"237-241","source":"Crossref","is-referenced-by-count":2,"title":["Adipofascial anterolateral thigh free flap in head and neck reconstruction: a case series"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6169-6345","authenticated-orcid":false,"given":"Joshua M","family":"Sorrentino","sequence":"first","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayham","family":"Al Afif","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William J","family":"Magner","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S Lynn","family":"Sigurdson","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason M","family":"Davies","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A","family":"Fenstermaker","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moleca","family":"Ghannam","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan P","family":"McSpadden","sequence":"additional","affiliation":[{"name":"Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, University of Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"key":"S0022215124001385_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2008.03.038"},{"key":"S0022215124001385_ref8","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1234023"},{"key":"S0022215124001385_ref7","doi-asserted-by":"crossref","first-page":"91","DOI":"10.5999\/aps.2013.40.2.91","article-title":"Adipofascial anterolateral thigh flap safety: applications and complications","volume":"40","author":"Agostini","year":"2013","journal-title":"Arch Plast Surg"},{"key":"S0022215124001385_ref16","doi-asserted-by":"publisher","DOI":"10.1177\/0194599818787801"},{"key":"S0022215124001385_ref10","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2019.08.01"},{"key":"S0022215124001385_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.wjorl.2020.01.004"},{"key":"S0022215124001385_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000645"},{"key":"S0022215124001385_ref2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21284"},{"key":"S0022215124001385_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.125.3.295"},{"key":"S0022215124001385_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30863"},{"key":"S0022215124001385_ref12","doi-asserted-by":"publisher","DOI":"10.7181\/acfs.2021.00290"},{"key":"S0022215124001385_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005975"},{"key":"S0022215124001385_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30870"},{"key":"S0022215124001385_ref13","first-page":"125","article-title":"Free flap reconstruction of the anterior skull base: A systematic review","volume":"83","author":"Dang","year":"2021","journal-title":"J Neurol Surg B Skull Base"},{"key":"S0022215124001385_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004404"},{"key":"S0022215124001385_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e328347f845"}],"container-title":["The Journal of Laryngology & 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