{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T02:27:54Z","timestamp":1775701674935,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215124001622_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>To evaluate the clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001622_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Eighty chronic dacryocystitis patients were randomly divided into two groups: observation (<jats:italic>n<\/jats:italic> = 39) and control (<jats:italic>n<\/jats:italic> = 41). Both groups underwent endoscopic dacryocystorhinostomy. The observation group used tobramycin dexamethasone eye ointment and catheter support, while the control group used only the eye ointment.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001622_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>No statistical differences were found in gender, age, disease course or eye type. However, the anastomotic formation time and bleeding amount were significantly different between the two groups (<jats:italic>p<\/jats:italic> &lt; 0.001). After six months of follow up, there were no significant complications differences (<jats:italic>p<\/jats:italic> &gt; 0.05). The fluorescein disappearance test time in the observation group was significantly shorter (<jats:italic>p<\/jats:italic> &lt; 0.001), and the clinical effective rate was significantly higher (97.4 per cent <jats:italic>vs<\/jats:italic> 78 per cent, <jats:italic>p<\/jats:italic> &lt; 0.05) in the observation group.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001622_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>Using tobramycin dexamethasone eye ointment combined with a catheter slightly prolongs the operation time and increases bleeding, but promotes anastomotic healing, accelerates tear drainage, improves the operation success rate and is economically efficient.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215124001622","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T09:56:32Z","timestamp":1729504592000},"page":"48-53","source":"Crossref","is-referenced-by-count":1,"title":["Clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy"],"prefix":"10.1017","volume":"139","author":[{"given":"Hailin","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoping","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yimin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junfang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1325-8126","authenticated-orcid":false,"given":"Wodong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,10,21]]},"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215124001622","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T09:52:20Z","timestamp":1741600340000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215124001622\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,21]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S0022215124001622"],"URL":"https:\/\/doi.org\/10.1017\/s0022215124001622","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,21]]}}}