{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T07:43:33Z","timestamp":1765439013474,"version":"3.41.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215124001671_sec1a\"><jats:title>Objectives<\/jats:title><jats:p>M\u00e9ni\u00e8re\u2019s disease is a chronic inner-ear disease attributed to endolymphatic hydrops. Magnetic resonance imaging with gadolinium allows visualisation of endolymphatic hydrops in vivo and may be an adjunct to diagnosis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001671_sec2b\"><jats:title>Methods<\/jats:title><jats:p>Thirty-eight patients suspected of having M\u00e9ni\u00e8re\u2019s disease underwent T2 weighted three-dimensional fluid-attenuated inversion recovery and true inversion recovery sequence magnetic resonance imaging 4 hours post double-dose intra-venous gadolinium. Presence of endolymphatic hydrops was graded by two radiologists at 0 and 4 months. Correlation to clinical diagnosis was assessed using Fisher\u2019s exact test.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001671_sec3c\"><jats:title>Results<\/jats:title><jats:p>Hydrops was identified in 88 per cent, 17 per cent and 27 per cent of patients with Definite M\u00e9ni\u00e8re\u2019s, Probable M\u00e9ni\u00e8re\u2019s and Undifferentiated disease, respectively. A significant correlation existed between diagnosis and presence of hydrops. Sensitivity and specificity were 88 per cent and 67 per cent, respectively. Intra- and inter-observer agreement for presence and grading of hydrops was near-perfect and substantial to near-perfect, respectively.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215124001671_sec4d\"><jats:title>Conclusion<\/jats:title><jats:p>Magnetic resonance imaging demonstrates radiographic hydrops with significant correlation to clinical diagnosis and good intra- and inter-observer agreement.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215124001671","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T09:18:32Z","timestamp":1729847912000},"page":"277-281","source":"Crossref","is-referenced-by-count":1,"title":["Delayed contrast MRI for the evaluation of M\u00e9ni\u00e8re\u2019s disease: an Australian perspective"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2191-0618","authenticated-orcid":false,"given":"Emily","family":"Barrett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Boeddinghaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Wedekind","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayse","family":"Tavora-Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jafri","family":"Kuthubutheen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,10,25]]},"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215124001671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T08:08:05Z","timestamp":1747987685000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215124001671\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,25]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S0022215124001671"],"URL":"https:\/\/doi.org\/10.1017\/s0022215124001671","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2024,10,25]]}}}