{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T04:58:22Z","timestamp":1771736302982,"version":"3.50.1"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215125000258_sec1a\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Radiomics refers to converting medical images into high-quality quantitative data. This review examines applications of radiomics in vestibular schwannomas and future considerations for translation into clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125000258_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The review was pre-registered on Prospero (ID: CRD42024579319). A comprehensive systematic review-informed search of the Ovid Medline, Embase and Global Health online databases was undertaken using the keywords \u2018acoustic neuroma\u2019 or \u2018vestibular schwannoma\u2019 or \u2018cerebellopontine angle tumour\u2019 or \u2018cerebellopontine tumour\u2019 or \u2018head and neck cancer\u2019 were combined with \u2018radiomic\u2019 or \u2018signature\u2019 or \u2018machine learning\u2019 or \u2018artificial intelligence\u2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125000258_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The studies (\n                      <jats:italic>n<\/jats:italic>\n                      = 6) were categorised into two groups: radiomics for pre-operative decision-making (\n                      <jats:italic>n<\/jats:italic>\n                      = 1) and radiomics for treatment outcomes (\n                      <jats:italic>n<\/jats:italic>\n                      = 5). Radiomic features were significantly associated with clinical outcomes. Radiomics-based predictive models were superior to expert vision.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125000258_sec4d\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Radiomics has potential for improving multiple aspects of vestibular schwannoma care, but lack of studies inhibited firm conclusions. Prospective studies are required to progress this field.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215125000258","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T02:38:37Z","timestamp":1743043117000},"page":"647-654","source":"Crossref","is-referenced-by-count":1,"title":["The application of radiomics in vestibular schwannomas"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2641-3279","authenticated-orcid":false,"given":"Terrenjit","family":"Gill","sequence":"first","affiliation":[{"name":"King\u2019s College London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Newcastle University"},{"name":"Freeman Hospital Newcastle upon Tyne Hospitals NHS Foundation Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9323-3107","authenticated-orcid":false,"given":"Amarkumar","family":"Rajgor","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, National Institute for Health & Care Research, Newcastle University"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Newcastle upon Tyne Hospitals NHS Foundation Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"key":"S0022215125000258_ref21","doi-asserted-by":"publisher","DOI":"10.1002\/mp.14308"},{"key":"S0022215125000258_ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"S0022215125000258_ref5","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20210499"},{"key":"S0022215125000258_ref4","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.141"},{"key":"S0022215125000258_ref20","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020191145"},{"key":"S0022215125000258_ref2","volume-title":"Acoustic Neuroma Market Size and Share Analysis \u2013 Growth Trends and Forecasts (2024 \u2013 2029)"},{"key":"S0022215125000258_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-018-4139-4"},{"key":"S0022215125000258_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/ons\/opx246"},{"key":"S0022215125000258_ref19","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020191145"},{"key":"S0022215125000258_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-017-1285-2"},{"key":"S0022215125000258_ref7","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-3102"},{"key":"S0022215125000258_ref13","volume-title":"Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy","author":"Hynes","year":"2023"},{"key":"S0022215125000258_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-009-9867-7"},{"key":"S0022215125000258_ref9","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-97865-5"},{"key":"S0022215125000258_ref17","doi-asserted-by":"publisher","DOI":"10.1002\/mp.14042"},{"key":"S0022215125000258_ref3","unstructured":"3 Mayo Clinic. 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Mayo Clinic United States: Mayo Clinic https:\/\/www.mayoclinic.org\/diseases-conditions\/acoustic-neuroma\/diagnosis-treatment\/drc-20356132; 2023"},{"key":"S0022215125000258_ref14","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002938"},{"key":"S0022215125000258_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.10.041"},{"key":"S0022215125000258_ref11","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13050808"},{"key":"S0022215125000258_ref1","volume-title":"Acoustic Neuroma (Vestibular Schwannomas)","author":"Jackson","year":"2023"},{"key":"S0022215125000258_ref16","doi-asserted-by":"publisher","DOI":"10.5430\/jst.v9n2p1"},{"key":"S0022215125000258_ref22","doi-asserted-by":"publisher","DOI":"10.1177\/1177932219899051"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215125000258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T03:59:42Z","timestamp":1771732782000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215125000258\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,27]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0022215125000258"],"URL":"https:\/\/doi.org\/10.1017\/s0022215125000258","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,27]]}}}