{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:05:18Z","timestamp":1761005118426,"version":"build-2065373602"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215125000271_sec1a\"><jats:title>Objectives<\/jats:title><jats:p>To explore methods for accurate diagnosis and effective treatment of otomycosis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215125000271_sec2b\"><jats:title>Methods<\/jats:title><jats:p>Using randomised stratification, eligible patients were split into a patient-applied medication group and a physician-applied medication group in order to compare the efficacy and recurrence rates of two treatment approaches.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215125000271_sec3c\"><jats:title>Results<\/jats:title><jats:p>The primary symptom of otomycosis was ear blockage (35.2 per cent), followed by pruritis (26.7 per cent) and otorrhea (13.6 per cent). Predominant fungi were <jats:italic>Aspergillus terreus<\/jats:italic> (50.5 per cent), <jats:italic>Candida parapsilosis<\/jats:italic> (15.5 per cent) and <jats:italic>Aspergillus niger<\/jats:italic> (12.5 per cent). The treatment efficacy was 44.7 per cent (34\/76) for the patient-applied medication group and 98.6 per cent (71\/72) for the physician-applied medication group, with the difference being statistically significant (\u03c7<jats:sup>2<\/jats:sup> = 52.061, <jats:italic>p<\/jats:italic> &lt;0.01). The recurrence rate was 35.3 per cent (12\/34) for the patient-applied group and 2.8 per cent (2\/71) for the physician-applied medication group, also showing a statistically significant difference (<jats:italic>p<\/jats:italic> &lt;0.01).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215125000271_sec4d\"><jats:title>Conclusion<\/jats:title><jats:p>Triamcinolone acetonide econazole cream application by a physician every 2\u20133 days, three times, effectively cures otomycosis and lowers recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215125000271","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T04:41:07Z","timestamp":1743396067000},"page":"820-825","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of the efficacy of patient self-application versus physician application of triamcinolone acetonide econazole cream in the treatment of otomycosis: a randomized open-label controlled trial"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6631-1440","authenticated-orcid":false,"given":"Chunsheng","family":"Ye","sequence":"first","affiliation":[{"name":"Zhongshan Hospital of Xiamen University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1579-4066","authenticated-orcid":false,"given":"Yongjun","family":"Hong","sequence":"additional","affiliation":[{"name":"Zhongshan Hospital of Xiamen University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahong","family":"Cai","sequence":"additional","affiliation":[{"name":"Jinjiang Municipal Hospital Jinnan Branch"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,3,31]]},"reference":[{"key":"S0022215125000271_ref12","doi-asserted-by":"publisher","DOI":"10.7874\/jao.2018.00276"},{"key":"S0022215125000271_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2486-0"},{"key":"S0022215125000271_ref2","first-page":"564","article-title":"Otomycosis; clinical features, predisposing factors and treatment implications","volume":"30","author":"Anwar","year":"2014","journal-title":"Pak J Med Sci"},{"key":"S0022215125000271_ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/636493"},{"key":"S0022215125000271_ref5","doi-asserted-by":"publisher","DOI":"10.1177\/014556130007900815"},{"key":"S0022215125000271_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116008598"},{"key":"S0022215125000271_ref14","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2020.1712474"},{"key":"S0022215125000271_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2011.02132.x"},{"key":"S0022215125000271_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.07.008"},{"key":"S0022215125000271_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-011-9427-5"},{"key":"S0022215125000271_ref7","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1055\/s-0038-1626702","article-title":"Identification of fungal pathogens in otomycosis and their drug sensitivity: our experience","volume":"22","author":"Ali","year":"2018","journal-title":"Int Arch Otorhinolaryngol"},{"key":"S0022215125000271_ref11","first-page":"721","article-title":"Bacterial and fungal organisms in otitis externa patients without fungal infection risk factors in Erzurum, Turkey","volume":"75","author":"Enoz","year":"2009","journal-title":"Braz J Otorhinolaryngol"},{"key":"S0022215125000271_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510009678X"},{"key":"S0022215125000271_ref13","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0507.2002.00737.x"},{"key":"S0022215125000271_ref10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0507.2001.00689.x"},{"key":"S0022215125000271_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29190"},{"key":"S0022215125000271_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.12.005"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215125000271","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T02:11:34Z","timestamp":1760926294000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215125000271\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,31]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S0022215125000271"],"URL":"https:\/\/doi.org\/10.1017\/s0022215125000271","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2025,3,31]]}}}