{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T04:58:17Z","timestamp":1771736297070,"version":"3.50.1"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215125000283_sec1a\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the efficacy and safety of the dumbbell-shaped tragal cartilage\u2013perichondrium air-filled chamber technique versus the gelatine sponge packing method for small\u2013medium tympanic membrane perforations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125000283_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of 68 patients (39 air-filled chamber, 29 gelatine sponge) treated between January 2020 and September 2024. Pre- and post-operative assessments included pure tone audiometry, air\u2013bone gap, tympanic membrane healing, and visual analogue scale scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125000283_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Healing rates were similar (89.7 per cent\n                      <jats:italic>vs<\/jats:italic>\n                      93.1 per cent,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.959). At six months, pure tone audiometry and air\u2013bone gap improvements were comparable (\n                      <jats:italic>p<\/jats:italic>\n                      &gt; 0.05). At one month, the air-filled chamber group showed better hearing recovery (pure tone audiometry: 19.71\n                      <jats:italic>vs<\/jats:italic>\n                      24.27 dB HL; air\u2013bone gap: 7.28\n                      <jats:italic>vs<\/jats:italic>\n                      12.28 dB HL; both\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05) and lower pain scores (1.13\n                      <jats:italic>vs<\/jats:italic>\n                      1.59,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.022). Complications and operative times were similar.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125000283_sec4d\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The air-filled chamber technique is a safe and effective alternative, offering superior early hearing recovery, reduced discomfort, and comparable long-term outcomes to the gelatine sponge method.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215125000283","type":"journal-article","created":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T08:45:17Z","timestamp":1743583517000},"page":"757-763","source":"Crossref","is-referenced-by-count":0,"title":["Clinical efficacy of the dumbbell-shaped tragal cartilage-perichondrium air-filled chamber technique for small-to-medium tympanic membrane perforations: a retrospective study"],"prefix":"10.1017","volume":"139","author":[{"given":"Chao","family":"Ji","sequence":"first","affiliation":[{"name":"Head and Neck Surgery, Nantong First People's Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9638-9978","authenticated-orcid":false,"given":"Fei-Fei","family":"Xu","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery, Nantong First People's Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"key":"S0022215125000283_ref7","first-page":"137","article-title":"Tragal perichondrium and composite cartilage graft complimenting endoscopic tympanoplasty in true sense: a comparison","volume":"33","author":"Varma","year":"2021","journal-title":"Iran J Otorhinolaryngol"},{"key":"S0022215125000283_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2020.102588"},{"key":"S0022215125000283_ref13","first-page":"317","article-title":"Biomedical application of materials for external auditory canal: history, challenges, and clinical prospects","volume":"39","author":"Xu","year":"2024","journal-title":"Bioact Mater"},{"key":"S0022215125000283_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-07186-6"},{"key":"S0022215125000283_ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-018-0289-4"},{"key":"S0022215125000283_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2022.103408"},{"key":"S0022215125000283_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/01945998211062153"},{"key":"S0022215125000283_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2023.09.003"},{"key":"S0022215125000283_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.381"},{"key":"S0022215125000283_ref4","doi-asserted-by":"publisher","DOI":"10.1080\/00016480701762508"},{"key":"S0022215125000283_ref14","doi-asserted-by":"publisher","DOI":"10.1088\/1748-605X\/abcf5d"},{"key":"S0022215125000283_ref16","first-page":"100046","article-title":"Tissue engineering and regenerative medicine strategies for the repair of tympanic membrane perforations","volume":"6","author":"Sainsbury","year":"2022","journal-title":"Biomater Biosyst"},{"key":"S0022215125000283_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.06.208"},{"key":"S0022215125000283_ref11","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11237000"},{"key":"S0022215125000283_ref12","doi-asserted-by":"publisher","DOI":"10.18203\/issn.2454-5929.ijohns20181873"},{"key":"S0022215125000283_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002628"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215125000283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T03:59:15Z","timestamp":1771732755000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215125000283\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,2]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0022215125000283"],"URL":"https:\/\/doi.org\/10.1017\/s0022215125000283","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,2]]}}}