{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:33:31Z","timestamp":1792020811096,"version":"4.4.0"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215125102624_sec1a\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyse the evolution of the vertigo index and its relationship with perceived disability in unilateral and bilateral M\u00e9ni\u00e8re\u2019s disease, assessing differences based on disease progression and clinical subtypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125102624_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A longitudinal descriptive study was conducted on unilateral and bilateral M\u00e9ni\u00e8re\u2019s disease patients, with data collected between 1977 and 2023 from two referral centres. Clinical and functional data were retrospectively reviewed to ensure compliance with updated diagnostic criteria. The vertigo index, integrating episode duration and frequency, quantified vertigo burden. Functional impact was assessed using the six-item American Academy of Otolaryngology Head and Neck Surgery disability scale, categorising patients into mild or moderate\/severe disability groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125102624_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Bilateral M\u00e9ni\u00e8re\u2019s disease patients had a higher proportion of moderate\/severe episodes (31.4 per cent) than unilateral M\u00e9ni\u00e8re\u2019s disease patients (11 per cent). In unilateral M\u00e9ni\u00e8re\u2019s disease patients, disability perception increased after 20 years of disease evolution. The vertigo index declined over time, except in later stages, where episodes were more disabling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125102624_sec4d\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings underscore the need for long-term follow up, particularly in bilateral M\u00e9ni\u00e8re\u2019s disease, where greater disability was observed. Disease management should adapt over time, addressing both vertigo burden and psycho-affective consequences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215125102624","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T06:31:42Z","timestamp":1750746702000},"page":"723-729","source":"Crossref","is-referenced-by-count":1,"title":["Beyond frequency: duration, intensity, and quality of life in M\u00e9ni\u00e8re\u2019s disease"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2884-5251","authenticated-orcid":false,"given":"Tom\u00e0s","family":"P\u00e9rez-Carbonell","sequence":"first","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valencia Universidad de Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Orts-Alborch","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valencia Universidad de Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanesa","family":"P\u00e9rez-Guil\u00e9n","sequence":"additional","affiliation":[{"name":"Hospital Universitario La Fe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Pla-Gil","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valencia Universidad de Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6275-7872","authenticated-orcid":false,"given":"Clara","family":"Espina-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Hospital del Mar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Aragon\u00e9s-Red\u00f3","sequence":"additional","affiliation":[{"name":"Hospital Arnau de Vilanova"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Marco-Algarra","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valencia Universidad de Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"S0022215125102624_ref11","doi-asserted-by":"publisher","DOI":"10.3233\/VES-150549"},{"key":"S0022215125102624_ref18","first-page":"265","article-title":"Informatics program in the study of patients with M\u00e9ni\u00e8re\u2019s vertigo [in Spanish]","volume":"19","author":"P\u00e9rez-Garrigues","year":"1992","journal-title":"An Otorrinolaringol Ibero Am"},{"key":"S0022215125102624_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200111000-00030"},{"key":"S0022215125102624_ref30","first-page":"428","article-title":"M\u00e9ni\u00e8re\u2019s disease, a survey of 408 patients","volume":"33","author":"Oosterveld","year":"1979","journal-title":"Acta Otorhinolaryngol Belg"},{"key":"S0022215125102624_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/000348940911800603"},{"key":"S0022215125102624_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3180caa14f"},{"key":"S0022215125102624_ref28","doi-asserted-by":"publisher","DOI":"10.3109\/00016489609124348"},{"key":"S0022215125102624_ref17","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215122001773"},{"key":"S0022215125102624_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(02)00028-2"},{"key":"S0022215125102624_ref16","first-page":"453","article-title":"Natural history of Meni\u00e8re\u2019s disease concerning 92 cases from 1971 to 1980 [in French]","volume":"110","author":"Charachon","year":"1989","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"S0022215125102624_ref26","doi-asserted-by":"publisher","DOI":"10.3109\/00016480903382808"},{"key":"S0022215125102624_ref4","first-page":"329","article-title":"Illness behaviour, personality traits, anxiety, and depression in patients with Meni\u00e8re\u2019s disease","volume":"25","author":"Savastano","year":"1996","journal-title":"J Otolaryngol"},{"key":"S0022215125102624_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-015-7930-1"},{"key":"S0022215125102624_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-022-07366-y"},{"key":"S0022215125102624_ref12","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.4.431"},{"key":"S0022215125102624_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.11.1149"},{"key":"S0022215125102624_ref8","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300501"},{"key":"S0022215125102624_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2016.02.006"},{"key":"S0022215125102624_ref19","first-page":"1","article-title":"Criterios diagn\u00f3sticos de enfermedad de Meni\u00e8re: Documento de consenso de la B\u00e1r\u00e1ny Society","volume":"67","author":"Lopez-Escamez","year":"2016","journal-title":"la Japan Society for Equilibrium Research, la European Academy of Otology and Neurotology (EAONO), la American Academy of Otolaryngology-Head and Neck Surgery. 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