{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T08:06:26Z","timestamp":1792397186736,"version":"4.4.0"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215125102995_sec1a\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Cholesteatoma is a pathological growth of squamous epithelium in the middle ear and mastoid. Pre-operative high-resolution computed tomography is commonly performed to guide the surgical approach and evaluate disease extent. The purpose of this review is to demonstrate the level of correlation between high-resolution computed tomography and intra-operative findings during cholesteatoma surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125102995_sec2b\">\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Medline, Embase and Cochrane databases were searched in December 2024 for studies comparing high-resolution computed tomography and intra-operative findings of adult patients diagnosed with cholesteatoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125102995_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 2514 abstracts identified, 15 were included. The correlation between pre-operative high-resolution computed tomography and intra-operative findings was strongest for the identification of erosion of the malleus (\n                      <jats:italic>k<\/jats:italic>\n                      = 0.77), followed by the lateral semicircular canal and tegmen tympani (\n                      <jats:italic>k<\/jats:italic>\n                      = 0.69). The weakest correlation was found for facial nerve dehiscence (\n                      <jats:italic>k<\/jats:italic>\n                      = 0.55).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215125102995_sec4d\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>High-resolution computed tomography is useful for providing a roadmap for surgery. It offers a strong correlation for intra-operative detection of malleus, incus, lateral semicircular canal and tegmen tympani involvement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215125102995","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T06:12:28Z","timestamp":1753769548000},"page":"2-11","source":"Crossref","is-referenced-by-count":2,"title":["Factors affecting the correlation between high-resolution computed tomography and operative findings in cholesteatoma surgery \u2013 a systematic review"],"prefix":"10.1017","volume":"140","author":[{"given":"G.","family":"Finch","sequence":"first","affiliation":[{"name":"University Hospitals Coventry and Warwickshire NHS Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5158-5895","authenticated-orcid":false,"given":"S.","family":"Patel","sequence":"additional","affiliation":[{"name":"Queen Elizabeth Hospital Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5208-6446","authenticated-orcid":false,"given":"B.","family":"Walters","sequence":"additional","affiliation":[{"name":"Sheffield Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Trotter","sequence":"additional","affiliation":[{"name":"University Hospitals Coventry and Warwickshire NHS Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,7,29]]},"reference":[{"key":"S0022215125102995_ref12","first-page":"7","article-title":"Comparison of preoperative temporal bone CT with intraoperative findings in patients with cholesteatoma","volume":"26","author":"Rogha","year":"2014","journal-title":"Iran J Otorhinolaryngol"},{"key":"S0022215125102995_ref14","first-page":"2303","article-title":"Pre-operative HRCT of middle ear pathology with particular reference to intra-operative findings in cholesteatoma","volume":"5","author":"Roy","year":"2023","journal-title":"Int J Acad Med Pharm"},{"key":"S0022215125102995_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2014.01.004"},{"key":"S0022215125102995_ref18","doi-asserted-by":"publisher","DOI":"10.5152\/etd.2015.0037"},{"key":"S0022215125102995_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2020.11.014"},{"key":"S0022215125102995_ref5","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2129"},{"key":"S0022215125102995_ref26","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215119001154"},{"key":"S0022215125102995_ref6","doi-asserted-by":"crossref","first-page":"328","DOI":"10.12659\/PJR.894155","article-title":"Computed tomography staging of middle ear cholesteatoma","volume":"80","author":"Razek","year":"2015","journal-title":"Pol J Radiol"},{"key":"S0022215125102995_ref27","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.75.898.750847"},{"key":"S0022215125102995_ref21","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000247824.90774.22"},{"key":"S0022215125102995_ref16","first-page":"313","article-title":"Role of HRCT temporal bones as a predictor of intra-operative findings in cases of CSOM: a prospective study","volume":"14","author":"Noule","year":"2023","journal-title":"Journal of Cardiovascular Disease Research"},{"key":"S0022215125102995_ref7","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-24-01"},{"key":"S0022215125102995_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2021.103198"},{"key":"S0022215125102995_ref3","first-page":"854024","article-title":"Updates and Knowledge Gaps in Cholesteatoma Research","volume":"2015","author":"Kuo","journal-title":"BioMed Res Int"},{"key":"S0022215125102995_ref15","first-page":"1664","article-title":"A study on correlation of preoperative HRCT finding with intraoperative findings in the evaluation of cholesteatoma","volume":"14","author":"Nayana","year":"2023","journal-title":"Journal of Cardiovascular Disease Research"},{"key":"S0022215125102995_ref17","first-page":"240","article-title":"Comparative evaluation between preoperative HRCT temporal bone findings and intraoperative findings in mastoid surgeries","volume":"14","author":"Patel","year":"2022","journal-title":"International Journal of Pharmaceutical and Clinical Research"},{"key":"S0022215125102995_ref23","first-page":"248039","article-title":"Imaging the facial nerve: a contemporary review","volume":"2013","author":"Gupta","year":"2013","journal-title":"Radiol Res Pract"},{"key":"S0022215125102995_ref20","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2004.442"},{"key":"S0022215125102995_ref1","unstructured":"1 Kennedy, KL , Singh, AK. 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