{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:06:15Z","timestamp":1788667575176,"version":"build-2803163510"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S002221512510409X_sec1a\">\n                    <jats:title>Problem<\/jats:title>\n                    <jats:p>Eustachian tube balloon dilation is increasingly recognised as a minimally invasive option for middle ear effusion. However, its role in children with cleft lip and palate remains under-explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S002221512510409X_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We prospectively evaluated 14 cleft lip and palate children (28 ears) with middle ear effusion. Group 1 (intervention) comprised 14 ears that underwent Eustachian tube balloon dilation with intranasal corticosteroids, while Group 2 (control) included 14 ears treated with intranasal corticosteroids alone. Tympanometry, pure-tone audiometry and Eustachian Tube Dysfunction Questionnaire-7 were administered before and six weeks after intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S002221512510409X_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eustachian tube balloon dilation significantly improved hearing thresholds (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.03) and air-bone gap (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.04), with favourable tympanometric changes (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05) and a significant reduction in Eustachian Tube Dysfunction Questionnaire-7 scores, indicating symptom improvement. No major complications occurred.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S002221512510409X_sec4d\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Eustachian tube balloon dilation is a safe, well-tolerated and potentially effective adjunctive procedure for cleft lip and palate children with middle ear effusion. Larger randomised controlled trials are needed to validate these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s002221512510409x","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T06:11:19Z","timestamp":1765433479000},"page":"159-165","source":"Crossref","is-referenced-by-count":1,"title":["Eustachian tube balloon dilation for middle ear effusion in children with cleft lip and palate"],"prefix":"10.1017","volume":"140","author":[{"given":"Samuel","family":"Abishegam","sequence":"first","affiliation":[{"name":"Universiti Malaya, Jalan Universiti"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1974-4379","authenticated-orcid":false,"given":"Jeyasakthy","family":"Saniasiaya","sequence":"additional","affiliation":[{"name":"Universiti Malaya, Jalan Universiti"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeyanthi","family":"Kulasegarah","sequence":"additional","affiliation":[{"name":"Universiti Malaya, Jalan Universiti"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"S002221512510409X_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1220-4"},{"key":"S002221512510409X_ref17","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003009"},{"key":"S002221512510409X_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(02)00206-9"},{"key":"S002221512510409X_ref2","volume-title":"Surgical Management of Otitis Media with Effusion in Children","year":"2008"},{"key":"S002221512510409X_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-017-4517-8"},{"key":"S002221512510409X_ref20","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000631"},{"key":"S002221512510409X_ref10","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23223"},{"key":"S002221512510409X_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-015-0050-5"},{"key":"S002221512510409X_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20950"},{"key":"S002221512510409X_ref8","first-page":"223","article-title":"Ventilation tubes in secretory otitis media associated with cleft palate: a retrospective analysis","volume":"37","author":"Civelek","year":"2007","journal-title":"Turk J Med Sci"},{"key":"S002221512510409X_ref5","doi-asserted-by":"publisher","DOI":"10.1597\/07-219.1"},{"key":"S002221512510409X_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/00034894211041340"},{"key":"S002221512510409X_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/pst.185"},{"key":"S002221512510409X_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.07.015"},{"key":"S002221512510409X_ref1","first-page":"S1","article-title":"Clinical practice guideline: otitis media with effusion (update)","volume":"154","author":"Rosenfeld","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"S002221512510409X_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29241"},{"key":"S002221512510409X_ref13","doi-asserted-by":"publisher","DOI":"10.1597\/15-047"},{"key":"S002221512510409X_ref21","doi-asserted-by":"publisher","DOI":"10.1177\/00034894231221888"},{"key":"S002221512510409X_ref3","unstructured":"3 SFORL. Prise en charge th\u00e9rapeutique des OSM de l\u2019enfant | Recommandations de pratiques cliniques. In: http:\/\/www.orlfrance.org\/download.php?id=319 [11 December 2025]"},{"key":"S002221512510409X_ref6","doi-asserted-by":"publisher","DOI":"10.3310\/hta19680"},{"key":"S002221512510409X_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2017.11.009"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221512510409X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T10:57:02Z","timestamp":1772449022000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221512510409X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,11]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S002221512510409X"],"URL":"https:\/\/doi.org\/10.1017\/s002221512510409x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,11]]}}}