{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:18:08Z","timestamp":1785417488834,"version":"3.56.0"},"reference-count":8,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215126104575_sec1a\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Drop attacks are a rare, debilitating symptom of M\u00e9ni\u00e8re\u2019s disease that affect an individual\u2019s physical and mental health. The aim of this series was to assess the response to treatment regimens in patients presenting with drop attacks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215126104575_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective case series of 8 patients with M\u00e9ni\u00e8re\u2019s disease and drop attacks was followed up for an average of 67 months (range, 17\u2013120 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215126104575_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients were initially managed with intratympanic steroids, with four patients having a complete response. The four non-responding patients were treated with intratympanic gentamicin, with one patient responding. Three patients were treated with triple canal occlusion. Two patients demonstrated drop attack resolution and one had a partial response. Seven out of 8 patients (87.5 per cent) suffered from depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215126104575_sec4d\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Steroid injections had a 50 per cent success rate in complete resolution of drop attacks. Gentamicin injections and triple semi-circular canal occlusion can bring benefits in patients failing steroid treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215126104575","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:45:58Z","timestamp":1774867558000},"page":"618-621","source":"Crossref","is-referenced-by-count":0,"title":["Managing drop attacks in patients with M\u00e9ni\u00e8re\u2019s disease"],"prefix":"10.1017","volume":"140","author":[{"given":"Campbell","family":"Mearns","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04y0x0x35","id-type":"ROR","asserted-by":"publisher"}],"name":"Queen Elizabeth University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5950-7728","authenticated-orcid":false,"given":"Alison","family":"Lim","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04y0x0x35","id-type":"ROR","asserted-by":"publisher"}],"name":"Queen Elizabeth University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Kontorinis","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04y0x0x35","id-type":"ROR","asserted-by":"publisher"}],"name":"Queen Elizabeth University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"S0022215126104575_ref2","doi-asserted-by":"publisher","DOI":"10.3233\/VES-201514"},{"key":"S0022215126104575_ref8","first-page":"CD008234","article-title":"Intratympanic gentamicin for M\u00e9ni\u00e8re\u2019s disease or syndrome","volume":"3","author":"Pullens","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"S0022215126104575_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31461-1"},{"key":"S0022215126104575_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/S002221512000081X"},{"key":"S0022215126104575_ref1","first-page":"1","article-title":"Management of drop attacks in M\u00e9ni\u00e8re\u2019s disease: a systematic literature review","volume":"21","author":"Selwyn","year":"2024","journal-title":"J Laryngol Otol"},{"key":"S0022215126104575_ref5","unstructured":"5 NHS Health Research Authority. Do I need NHS REC review? In: http:\/\/www.hra-decisiontools.org.uk\/ethics\/ [ May 2025 ]"},{"key":"S0022215126104575_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-022-07368-w"},{"key":"S0022215126104575_ref6","doi-asserted-by":"publisher","DOI":"10.1017\/S002221512100387X"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215126104575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T07:01:14Z","timestamp":1784271674000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215126104575\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,30]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0022215126104575"],"URL":"https:\/\/doi.org\/10.1017\/s0022215126104575","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,30]]}}}