{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:48:16Z","timestamp":1756309696931},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2007,2,28]],"date-time":"2007-02-28T00:00:00Z","timestamp":1172620800000},"content-version":"unspecified","delay-in-days":2860,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Proc. Nutr. Soc."],"published-print":{"date-parts":[[1999,5]]},"abstract":"<jats:p>In early epidemiological studies of diet and cancer the stress was on the search for causal factors. Population (ecological) studies tended to show a strong correlation between meat intake, particularly red meat, and the risk of colo-rectal cancer. They also tended to show meat to be strongly inversely correlated with cancers of the stomach and oesophagus and liver. Early case- control studies tended to support the postulated role for red meat in colo-rectal carcinogenesis, although more recent case-control studies, particularly those from Europe, have tended to show no relationship. The cohort studies in general failed to detect any relationship between meat intake and colo-rectal cancer risk. The available evidence points to the intake of protective factors such as vegetables and whole-grain cereals being the main determinants of colo-rectal cancer risk, with meat intake only coincidentally related.<\/jats:p>","DOI":"10.1017\/s002966519900035x","type":"journal-article","created":{"date-parts":[[2011,2,25]],"date-time":"2011-02-25T06:17:50Z","timestamp":1298614670000},"page":"261-264","source":"Crossref","is-referenced-by-count":15,"title":["Meat and colo-rectal cancer"],"prefix":"10.1017","volume":"58","author":[{"given":"Michael J.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,2,28]]},"reference":[{"key":"S002966519900035X_ref007","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19970703)72:1<56::AID-IJC8>3.0.CO;2-3"},{"key":"S002966519900035X_ref006","first-page":"132","article-title":"Chemoprevention of metachronous adenomas of the large bowel: design and interim results of a randomised trial of calcium and fibre","volume":"6","author":"Faivre","year":"1997","journal-title":"European Journal of Cancer Prevention"},{"key":"S002966519900035X_ref015","doi-asserted-by":"publisher","DOI":"10.1007\/BF01624579"},{"key":"S002966519900035X_ref010","first-page":"718","article-title":"A prospective cohort study on the relation between meat consumption and the risk of colon cancer","volume":"54","author":"Goldbohm","year":"1994","journal-title":"Cancer Research"},{"key":"S002966519900035X_ref023","doi-asserted-by":"publisher","DOI":"10.1080\/01635588709513956"},{"key":"S002966519900035X_ref020","volume-title":"Mortality from Smoking in Developed Countries 1950\u20132000","author":"Peto","year":"1994"},{"key":"S002966519900035X_ref003","doi-asserted-by":"publisher","DOI":"10.1007\/BF01830725"},{"key":"S002966519900035X_ref014","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910590608"},{"key":"S002966519900035X_ref013","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-199710000-00001"},{"key":"S002966519900035X_ref017","volume-title":"Household Food Consumption and Expenditure, 1970. 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