{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T12:45:06Z","timestamp":1774788306161,"version":"3.50.1"},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"S1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":5150,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1995,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Several years have elapsed since the publication by Johnson <jats:italic>et al.<\/jats:italic> (1989) of the cloning of a recombinant antigen from the cestode parasite <jats:italic>Taenia ovis<\/jats:italic> which stimulated high levels of protective immunity in sheep. A great deal of subsequent research and development was necessary to bring the fledgling vaccine to the point of being a registered commercial product. The results of these subsequent studies are dealt with briefly in this paper, including the results of field trials. The <jats:italic>T. ovis<\/jats:italic> vaccine was registered by the New Zealand Animal Remedies Board in February 1994. Where then is the commercial product ? This paper gives a background to market problems which have emerged through the politics (and realities) of the NZ <jats:italic>T. ovis<\/jats:italic> control campaign. It serves as notice that the best science dedicated to producing vaccines or products for parasitic, or other, diseases often faces significant hurdles in the real world of commerce and politics.<\/jats:p>","DOI":"10.1017\/s0031182000001438","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T09:46:15Z","timestamp":1244195175000},"page":"S5-S10","source":"Crossref","is-referenced-by-count":41,"title":["<i>Taenia ovis<\/i> recombinant vaccine \u2013 \u2018<i>quo vadit<\/i>\u2019"],"prefix":"10.1017","volume":"110","author":[{"given":"M. D.","family":"Rickard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. B. L.","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. D.","family":"Heath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. W.","family":"Lightowlers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000001438_ref005","doi-asserted-by":"publisher","DOI":"10.1038\/338585a0"},{"key":"S0031182000001438_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000066841"},{"key":"S0031182000001438_ref004","unstructured":"Heath D. D. , Lawrence S. B. , Ralston M. J. , Harrison G. B. L. , Dempster R. P. , Robinson C. , Lightowlers M. W. , Gaucci C. & Newton S. (1993). New protective cloned antigens of Taenia ovis . Proceedings of the New Zealand Society for Parasitology, August, 1993."},{"key":"S0031182000001438_ref011","first-page":"3","volume-title":"New Strategies in Parasitology","author":"Rickard","year":"1989"},{"key":"S0031182000001438_ref010","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1993.50"},{"key":"S0031182000001438_ref002","volume-title":"Proceedings of Vaccines","author":"Harrison","year":"1993"},{"key":"S0031182000001438_ref003","unstructured":"Harrison G. , Robinson C. , Wakelin R. , Lawrence S. & Heath D. (1993 c). Field trials with recombinant Taenia ovis vaccine. Proceedings of the Australian Society for Parasitology, September 1993."},{"key":"S0031182000001438_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(93)90096-H"},{"key":"S0031182000001438_ref006","unstructured":"Lawrence S. B. , Harrison G. B. L. , Robinson C. M. & Heath D. D. (1993). Vaccination of lambs against Taenia ovis in the presence of maternal antibody. Proceedings of the New Zealand Society for Parasitology, August, 1993."},{"key":"S0031182000001438_ref009","first-page":"171","volume-title":"Animal Parasite Control Utilising Biotechnology","author":"Lightowlers","year":"1992"},{"key":"S0031182000001438_ref007","doi-asserted-by":"publisher","DOI":"10.1080\/03014223.1994.9517978"},{"key":"S0031182000001438_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60277-8"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000001438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T15:02:15Z","timestamp":1557846135000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000001438\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3]]},"references-count":12,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[1995,3]]}},"alternative-id":["S0031182000001438"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000001438","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,3]]}}}