{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:32:56Z","timestamp":1784194376041,"version":"3.55.0"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":12118,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1976,2]]},"abstract":"<jats:p>Lethal irradiation (850 rads) of mice made resistant to<jats:italic>Trichuris muris<\/jats:italic>markedly depressed their ability to expel a challenge infection. Expulsion was restored within 7\u201310 days when MLNC from uninfected mice were transferred on the day of infection, but no significant restoration was evident after transfer of immune serum. Transfer of BM alone had no restorative effect within 10 days and no synergism was seen when both BM and MLNC were transferred. MLNC from uninfected donors did not restore challenge expulsion when transfer was delayed until day 7 and the mice were killed 3 days later, although MLNC from resistant donors were effective within this time. When irradiated mice were given BM and the challenge infection allowed to continue for 15 days expulsion was restored, as it was when challenge was delayed for 7 days after BM transfer in thymectomized mice. The results confirm that expulsion of<jats:italic>T. muris<\/jats:italic>involves both antibody-mediated and lymphoid cell-mediated phases and offer no evidence for the involvement of other cell types.<\/jats:p>","DOI":"10.1017\/s0031182000058455","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:06:31Z","timestamp":1244217991000},"page":"41-50","source":"Crossref","is-referenced-by-count":11,"title":["Immune expulsion of<i>Trichuris muris<\/i>from resistant mice: suppression by irradiation and restoration by transfer of lymphoid cells"],"prefix":"10.1017","volume":"72","author":[{"given":"D.","family":"Wakelin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendoline R.","family":"Selby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000058455_ref018","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000044528"},{"key":"S0031182000058455_ref016","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000072395"},{"key":"S0031182000058455_ref014","first-page":"788","article-title":"Effect of irradiation on established delayed hypersensitivity","volume":"80","author":"Visakorpi","year":"1972","journal-title":"Acta pathologica et microbiologica scandinavica"},{"key":"S0031182000058455_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(73)90062-3"},{"key":"S0031182000058455_ref008","doi-asserted-by":"crossref","first-page":"138","DOI":"10.4049\/jimmunol.114.1_Part_1.138","article-title":"Host-derived antibody-forming cells in lethally irradiated mice","volume":"114","author":"Pilarski","year":"1975","journal-title":"Journal of Immunology"},{"key":"S0031182000058455_ref007","first-page":"33","article-title":"Studies on the differentiation of B lymphocytes in the mouse","volume":"25","author":"Nossal","year":"1973","journal-title":"Immunology"},{"key":"S0031182000058455_ref006","first-page":"3","article-title":"Thymus and antigen reactive cells","volume":"1","author":"Miller","year":"1969","journal-title":"Transplantation Reviews"},{"key":"S0031182000058455_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60321-8"},{"key":"S0031182000058455_ref003","first-page":"147","article-title":"The acute effects of ionizing radiation on antibody-producing cells (PFC) in mouse spleen during primary and secondary responses to sheep erythrocytes (SRC)","volume":"23","author":"Harris","year":"1972","journal-title":"Immunology"},{"key":"S0031182000058455_ref019","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000052173"},{"key":"S0031182000058455_ref002","first-page":"449","article-title":"Persistence of pre-irradiation immunity to Hymenolepis nana in syngeneic chimaeras: influence of radiation dose and time of marrow injection","volume":"17","author":"Friedberg","year":"1970","journal-title":"International Journal of Radiation Biology"},{"key":"S0031182000058455_ref001","doi-asserted-by":"publisher","DOI":"10.1159\/000231075"},{"key":"S0031182000058455_ref009","first-page":"579","article-title":"Crossreactions between erythrocytes at the T-cell level","volume":"24","author":"Playfair","year":"1973","journal-title":"Immunology"},{"key":"S0031182000058455_ref011","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053166"},{"key":"S0031182000058455_ref020","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(74)90030-7"},{"key":"S0031182000058455_ref005","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1040690312"},{"key":"S0031182000058455_ref013","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700640403"},{"key":"S0031182000058455_ref012","volume-title":"Radiation and Immune Response","author":"Taliaferro","year":"1964"},{"key":"S0031182000058455_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/0008-8749(73)90010-5"},{"key":"S0031182000058455_ref015","doi-asserted-by":"crossref","first-page":"846","DOI":"10.4049\/jimmunol.101.5.846","article-title":"Recovery of delayed-type hypersensitivity in mice following suppressive doses of X-radiation","volume":"101","author":"Volkman","year":"1968","journal-title":"Journal of Immunology"},{"key":"S0031182000058455_ref017","first-page":"162","article-title":"The stimulation of immunity and the induction of unresponsiveness to Trichuris muris in various strains of laboratory mice","volume":"35","author":"Wakelin","year":"1970","journal-title":"Zeitschrift f\u00fcur Parasitologic"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000058455","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T09:15:59Z","timestamp":1710407759000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000058455\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,2]]},"references-count":21,"aliases":["10.1017\/s0031182000043171"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[1976,2]]}},"alternative-id":["S0031182000058455"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000058455","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,2]]}}}