{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T08:27:12Z","timestamp":1698136032720},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":12910,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1973,12]]},"abstract":"<jats:p>Alteration of the free amino acid pool of<jats:italic>Hymenolepis diminuta<\/jats:italic>was observed following incubation of worms with a single exogenous amino acid<jats:italic>in vitro<\/jats:italic>, recovery from which depended upon the initial magnitude of alteration. The free amino acid pool of both rat small intestine and<jats:italic>H. diminuta<\/jats:italic>was rendered imbalanced after feeding a single dietary dose of proline. Recovery was more rapid in the host than in the parasite tissues. The quantitative dynamics of amino acid change with time were examined. The effects of amino acid variation upon the uptake and incorporation of lysine-C<jats:sup>14<\/jats:sup>into worm protein were examined<jats:italic>in vitro<\/jats:italic>. Four amino acids altered lysine incorporation; aspartate stimulated incorporation while ornithine, arginine and histidine reduced variously the absolute amount of lysine uptake but produced relative stimulation of lysine incorporation. These data indicate that, in the system examined, short term variation of the free amino acid pool is unlikely to affect protein synthesis in<jats:italic>H. diminuta<\/jats:italic>. Data were obtained suggesting the possible occurrence of certain amino acid inter conversions in<jats:italic>H. diminuta<\/jats:italic>.<\/jats:p>","DOI":"10.1017\/s0031182000046527","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:12:40Z","timestamp":1244203960000},"page":"289-305","source":"Crossref","is-referenced-by-count":9,"title":["Studies on the free pool of amino acids of the cestode<i>Hymenolepis diminuta<\/i>"],"prefix":"10.1017","volume":"67","author":[{"given":"L. H.","family":"Chappell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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Enzymatic cleavage of argininosuccinic acid to arginine and fumaric acid","volume":"204","author":"Ratner","year":"1953","journal-title":"Journal of Biological Chemistry"},{"key":"S0031182000046527_ref022","doi-asserted-by":"publisher","DOI":"10.2307\/3276830"},{"key":"S0031182000046527_ref023","doi-asserted-by":"publisher","DOI":"10.2307\/3277301"},{"key":"S0031182000046527_ref024","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1963.tb40664.x"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000046527","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T22:39:15Z","timestamp":1633559955000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000046527\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,12]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1973,12]]}},"alternative-id":["S0031182000046527"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000046527","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,12]]}}}