{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T06:42:12Z","timestamp":1770705732607,"version":"3.49.0"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":11814,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1976,12]]},"abstract":"<jats:p>The course of infection with a local strain of <jats:italic>Schistosoma mansoni<\/jats:italic> was investigated in Kenyan baboons (<jats:italic>Papio anubis<\/jats:italic>). A single exposure to 5000 cercariae per baboon (cpb) killed five 4\u20138 kg baboons; a sixth survived the full 30-week post-exposure period, with suppressed egg production after week 11. Lower doses were not lethal. A single exposure to 1000 cpb gave satisfactory adult worm recoveries, high and steady faecal egg excretion, and a high tissue egg recovery, predominantly from the large intestine. A similar but less consistent picture was obtained with a single exposure to 200 cpb. Baboons receiving 5 monthly exposures of 200 cpb (1000 cpb total) showed some evidence of the development of protective immunity. Three animals showed patterns resembling those for 200 and 1000 cpb. The other 3 had suppressed egg production (faecal and tissue) indicating, perhaps, some immunological process. They also had an abnormally high percentage of eggs in the liver.<\/jats:p>","DOI":"10.1017\/s003118200004693x","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:55:28Z","timestamp":1244220928000},"page":"239-252","source":"Crossref","is-referenced-by-count":57,"title":["<i>Schistosoma mansoni<\/i> in the baboon <i>(Papio anubis)<\/i>: parasitological responses of Kenyan baboons to different exposures of a local parasite strain"],"prefix":"10.1017","volume":"73","author":[{"given":"R. F.","family":"Sturrock","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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Preliminary observations on the susceptibility of the baboon Papio anubis to Schistosoma haematobium and Schistosoma mansoni","volume":"37","author":"Jordan","year":"1967","journal-title":"Bulletin of the World Health Organization"},{"key":"S003118200004693X_ref026","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1974.23.902"},{"key":"S003118200004693X_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(69)90122-9"},{"key":"S003118200004693X_ref027","first-page":"77","volume-title":"9th Symposium of British Society for Parasitology","author":"Webbe","year":"1971"},{"key":"S003118200004693X_ref028","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/124.6.613"},{"key":"S003118200004693X_ref029","first-page":"553","article-title":"The immunology of schistosomiasis","volume":"51","year":"1974","journal-title":"Bulletin of the World Health Organization"},{"key":"S003118200004693X_ref023","first-page":"225","article-title":"The cellophane thick-smear technique in comparison with the filtration staining technique for the quantitative determination of Schistosoma mansoni ova in stools","volume":"2","author":"Terpstra","year":"1975","journal-title":"East African Journal of Medical Research"},{"key":"S003118200004693X_ref004","first-page":"95","article-title":"Schistosoma mansoni in baboons. 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