{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T04:29:50Z","timestamp":1759638590125},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":11632,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1977,6]]},"abstract":"<jats:p>When mice were irradiated immediately before infection with<jats:italic>Trichinella spiralis<\/jats:italic>there was a profound and long-lasting interference with their ability to expel adult worms from the intestine. Irradiation given after the fifth day of infection was progressively less effective in this respect. The ability to expel worms was not restored when mesenteric lymph node cells (MLNC) were transferred (<jats:italic>a<\/jats:italic>) on the day of infection in mice irradiated one day previously, or (<jats:italic>b<\/jats:italic>) on day 7 of an infection in mice irradiated on day 6, even though the MLNC transferred immunity to intact recipients. Transfer of bone marrow (BM) alone was also without effect. However, worm explusion was restored if, following irradiation and injection of BM, 10 days were allowed for BM differentiation before transfer of MLNC. This restoration was effective even after lethal levels of irradiation and was clearly dependent upon a donor-derived BM component cooperating with, or responding to, the activity of the transferred MLNC. The possibility that the BM component is non-lymphoid in nature is discussed.<\/jats:p>","DOI":"10.1017\/s0031182000047855","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:54:56Z","timestamp":1244220896000},"page":"225-234","source":"Crossref","is-referenced-by-count":18,"title":["Evidence for the involvement of a bone marrow-derived cell population in the immune expulsion of<i>Trichinella spiralis<\/i>"],"prefix":"10.1017","volume":"74","author":[{"given":"D.","family":"Wakelin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret M.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000047855_ref002","volume-title":"The White Cell","author":"Cline","year":"1975"},{"key":"S0031182000047855_ref003","doi-asserted-by":"publisher","DOI":"10.1159\/000231075"},{"key":"S0031182000047855_ref010","first-page":"7","article-title":"The immune mechanism which expels the intestinal stage of Trichinella spiralis from rats","volume":"30","author":"Love","year":"1976","journal-title":"Immunology"},{"key":"S0031182000047855_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(74)90030-7"},{"key":"S0031182000047855_ref015","first-page":"173","article-title":"Immunity to primary and challenge infections Trichinella spiralis in mice: a re-examination of conventional parameters","volume":"72","author":"Wakelin","year":"1976","journal-title":"Paratisology"},{"key":"S0031182000047855_ref014","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000049507"},{"key":"S0031182000047855_ref007","doi-asserted-by":"publisher","DOI":"10.1159\/000231076"},{"key":"S0031182000047855_ref018","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000047843"},{"key":"S0031182000047855_ref011","first-page":"147","article-title":"Cooperation between antibodies and cells in immunity to a nematode parasite","volume":"19","author":"Ogilvie","year":"1974","journal-title":"Transplantation Reviews"},{"key":"S0031182000047855_ref004","first-page":"367","volume-title":"Trichinellosis","author":"Gore","year":"1973"},{"key":"S0031182000047855_ref019","first-page":"29","article-title":"The influence of X-irradiation on the immunity of mice to infection with Trichinella spiralis","volume":"78","author":"Yarinsky","year":"1962","journal-title":"Journal of the Elisha Mitchell Scientific Society"},{"key":"S0031182000047855_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(75)90077-6"},{"key":"S0031182000047855_ref001","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.4049\/jimmunol.112.4.1407","article-title":"Requirement for bone marrow-derived cells in resistance to Listeria","volume":"112","author":"Campbell","year":"1974","journal-title":"Journal of Immunology"},{"key":"S0031182000047855_ref009","first-page":"133","article-title":"Studies on delayed (cellular) hypersensitivity in mice infected with Trichinella spiralis. 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Transfer of lymph node cells","volume":"80","author":"Larsh","year":"1964","journal-title":"Journal of the Elisha Mitchell Scientific Society"},{"key":"S0031182000047855_ref017","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000043171"},{"key":"S0031182000047855_ref005","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1128\/IAI.11.5.949-954.1975","article-title":"Requirement for a bone marrow-derived component in the expression of cell-mediated antibacterial immunity","volume":"11","author":"Hahn","year":"1975","journal-title":"Infection and Immunity"},{"key":"S0031182000047855_ref013","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000052173"},{"key":"S0031182000047855_ref006","first-page":"767","article-title":"Protective immunity to Nippostrongylus brasiliensis in the rat: central role of the lymphocyte in worm expulsion","volume":"22","author":"Keller","year":"1972","journal-title":"Immunology"},{"key":"S0031182000047855_ref012","volume-title":"Radiation and Immune Mechanisms","author":"Taliaferro","year":"1964"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000047855","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T14:39:49Z","timestamp":1685025589000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000047855\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,6]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1977,6]]}},"alternative-id":["S0031182000047855"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000047855","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,6]]}}}