{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T19:16:01Z","timestamp":1699643761513},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":11267,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1978,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Rats were treated with betamethasone at different stages of infection with<jats:italic>Strongyloides ratti<\/jats:italic>. Treatment caused a diminution in the number of adult worms recovered but this residual population was not expelled as were worms from untreated rats. If treatment was started after expulsion had already begun adult worm numbers increased \u2013 suggesting that auto-infection occurred. Treatment throughout a primary infection prevented the development of an immune response which expelled, or killed, a challenge infection. Treatment, just before and just after challenge, prevented the expulsion of the challenge infection. Worm expulsion up to day 35 was prevented by treating rats with betamethasone 4, 6, 8 and 10 days after infection.<\/jats:p>","DOI":"10.1017\/s0031182000048162","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:03:43Z","timestamp":1244203423000},"page":"289-298","source":"Crossref","is-referenced-by-count":11,"title":["<i>Strongyloides ratti<\/i>: the effect of betamethasone on the course of infection in rats"],"prefix":"10.1017","volume":"76","author":[{"given":"R.","family":"Moqbel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. A.","family":"Denham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000048162_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90481-1"},{"key":"S0031182000048162_ref014","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-72-2-199"},{"key":"S0031182000048162_ref015","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1966.03100080125044"},{"key":"S0031182000048162_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0008-8749(72)90255-9"},{"key":"S0031182000048162_ref008","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1957.6.553"},{"key":"S0031182000048162_ref012","doi-asserted-by":"publisher","DOI":"10.2307\/3275272"},{"key":"S0031182000048162_ref006","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196611172752003"},{"key":"S0031182000048162_ref011","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1017\/S0031182000086285","article-title":"Use of cortisone derivatives to inhibit resistance to Nippostrongylus brasiliensis and to study the fate of parasites in resistant hosts","volume":"55","author":"Ogilvie","year":"1965","journal-title":"Parasitology"},{"key":"S0031182000048162_ref002","doi-asserted-by":"publisher","DOI":"10.2307\/3275772"},{"key":"S0031182000048162_ref004","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/98.1.39"},{"key":"S0031182000048162_ref001","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053191"},{"key":"S0031182000048162_ref016","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000078070"},{"key":"S0031182000048162_ref009","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X0000763X"},{"key":"S0031182000048162_ref007","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/102.2.158"},{"key":"S0031182000048162_ref003","doi-asserted-by":"publisher","DOI":"10.1007\/BF02239276"},{"key":"S0031182000048162_ref018","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1955.4.61"},{"key":"S0031182000048162_ref005","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5843.771"},{"key":"S0031182000048162_ref017","first-page":"1","article-title":"The induction of immunological tolerance to the parasitic nematode Trichuris muris in cortisone-treated mice","volume":"26","author":"Wakelin","year":"1974","journal-title":"Immunology"},{"key":"S0031182000048162_ref019","first-page":"245","article-title":"Fatal strongyloidiasis in Hodgkin's disease after immunosuppressive therapy","volume":"73","author":"Yim","year":"1970","journal-title":"Journal of Tropical Medicine and Hygiene"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000048162","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T06:14:23Z","timestamp":1589868863000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000048162\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,6]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1978,6]]}},"alternative-id":["S0031182000048162"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000048162","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,6]]}}}