{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:05:40Z","timestamp":1780934740004,"version":"3.54.1"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":12058,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1976,4]]},"abstract":"<jats:p>In young (6- to 8-week-old) NTH strain inbred mice expulsion of a primary infection of <jats:italic>Trichinella spiralis<\/jats:italic> began on day 8 and was virtually complete by day 11\u00b75. In older mice expulsion occurred 1 or 2 days earlier. Experience of a primary infection elicited strong immunity to challenge, whether the challenge was given immediately after worm expulsion (day 14) or delayed (day 42). Challenge infections were expelled rapidly, the majority of worms being lost during the first day. Immunity to challenge was elicited by low-level primary infections and was effective against large challenge infections. These results are discussed in relation to conventionally accepted parameters of immunity to <jats:italic>T. spiralis<\/jats:italic> in mice which, it is considered, are applicable only to mice with a genetically-determined low-level of responsiveness to the parasite.<\/jats:p>","DOI":"10.1017\/s0031182000048472","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:57:30Z","timestamp":1244206650000},"page":"173-182","source":"Crossref","is-referenced-by-count":124,"title":["Immunity to primary and challenge infections of <i>Trichinella spiralis<\/i> in mice: a re-examination of conventional parameters"],"prefix":"10.1017","volume":"72","author":[{"given":"D.","family":"Wakelin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Lloyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000048472_ref030","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000047156"},{"key":"S0031182000048472_ref029","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053142"},{"key":"S0031182000048472_ref027","first-page":"571","article-title":"Degree of resistance of some mouse strains to Trichinella spiralis infection","volume":"15","author":"Stefanski","year":"1969","journal-title":"Wiadomo\u015bci Parazytologiczne"},{"key":"S0031182000048472_ref026","doi-asserted-by":"publisher","DOI":"10.2307\/3278557"},{"key":"S0031182000048472_ref024","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/88.3.248"},{"key":"S0031182000048472_ref023","doi-asserted-by":"publisher","DOI":"10.2307\/3277063"},{"key":"S0031182000048472_ref022","first-page":"35","article-title":"Rapid loss of Trichinella spiralis fed to immune rats and its bearing on the mechanism of immunity","volume":"24","author":"McCoy","year":"1938","journal-title":"Journal of Parasitology"},{"key":"S0031182000048472_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(72)90107-5"},{"key":"S0031182000048472_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(63)90005-5"},{"key":"S0031182000048472_ref025","first-page":"205","volume-title":"Trichinellosis","author":"Ruitenberg","year":"1974"},{"key":"S0031182000048472_ref014","first-page":"367","volume-title":"Trichinellosis","author":"Gore","year":"1974"},{"key":"S0031182000048472_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(72)90100-2"},{"key":"S0031182000048472_ref028","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-80-19674"},{"key":"S0031182000048472_ref020","unstructured":"Love R. 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