{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T11:32:35Z","timestamp":1779017555107,"version":"3.51.4"},"reference-count":40,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":9926,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1982,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The processes which govern the age structure of <jats:italic>Fasciola hepatica<\/jats:italic> populations in sheep were investigated by means of a simple mathematical model. The mortality of the metacercariae on the pasture was shown to be a factor of major importance. The mortality rate depends on the micro-climate that prevails at the pasture surface, and thus the age distribution curve of a population of flukes is also determined in part by the weather. This has important implications for the chemotherapy of fascioliasis: flukicides are not equally effective over the whole range of age-classes of parasite and so the factors which govern the age distribution curve of the parasite population within individual hosts ultimately determine the efficiency of chemotherapy.<\/jats:p>","DOI":"10.1017\/s0031182000051659","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:40:22Z","timestamp":1244205622000},"page":"49-61","source":"Crossref","is-referenced-by-count":18,"title":["An analysis of variations in the age structure of <i>Fasciola hepatica<\/i> populations in sheep"],"prefix":"10.1017","volume":"84","author":[{"given":"Gary","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000051659_ref009","first-page":"675","article-title":"Fascioliasis in Australia","volume":"87","author":"Boray","year":"1977","journal-title":"Bulletin de l'Office International des Epizooties"},{"key":"S0031182000051659_ref019","first-page":"22","volume-title":"Facts and Reflections II. 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