{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:45:26Z","timestamp":1778874326526,"version":"3.51.4"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":12363,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1975,6]]},"abstract":"<jats:p>Immune serum accelerated the expulsion of <jats:italic>Trichuris muris<\/jats:italic> when transferred into normal mice on days 0 and 3 after infection, but had no effect when the recipient mice had been immunosuppressed by sublethal irradiation or by cortisone treatment. Delaying serum transfer until days 7 and 8 in normal mice failed to accelerate expulsion, although immune mesenteric lymph node cells (MLNC) accelerated expulsion whether transferred early or late in infection.<\/jats:p><jats:p>Expulsion from NIH mice, normally complete by 12 days, was prevented by sublethal irradiation given as late as 9 days after infection, but could be restored by subsequent transfer of immune MLNC or, to a lesser degree, non-immune MLNC. Immune MLNC were unable to restore worm expulsion in mice irradiated before infection.<\/jats:p><jats:p>These results are interpreted as showing that the immune expulsion of <jats:italic>T. muris<\/jats:italic> from mice during a primary infection requires the sequential activities of antibody-mediated and lymphoid cell-mediated components.<\/jats:p>","DOI":"10.1017\/s0031182000052173","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:59:07Z","timestamp":1244206747000},"page":"397-405","source":"Crossref","is-referenced-by-count":45,"title":["Immune expulsion of <i>Trichuris muris<\/i> from mice during a primary infection: analysis of the components involved"],"prefix":"10.1017","volume":"70","author":[{"given":"D.","family":"Wakelin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000052173_ref011","first-page":"155","volume-title":"Immunity to Parasitic Animals","author":"Murray","year":"1972"},{"key":"S0031182000052173_ref009","doi-asserted-by":"publisher","DOI":"10.1159\/000231076"},{"key":"S0031182000052173_ref014","volume-title":"Radiation and Immune Mechanisms","author":"Taliaferro","year":"1964"},{"key":"S0031182000052173_ref006","first-page":"147","article-title":"The acute effects of ionizing radiation on antibody-producing cells (PFC) in mouse spleen during primary and secondary responses to sheep erythrocytes (SRC)","volume":"23","author":"Harris","year":"1972","journal-title":"Immunology"},{"key":"S0031182000052173_ref005","first-page":"467","article-title":"Expulsion of Nippostrongylus brasiliensis from the intestine of rats: collaboration between humoral and cellular components of the immune response","volume":"24","author":"Dineen","year":"1973","journal-title":"Immunology"},{"key":"S0031182000052173_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(74)90030-7"},{"key":"S0031182000052173_ref010","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1040690312"},{"key":"S0031182000052173_ref015","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700640403"},{"key":"S0031182000052173_ref002","doi-asserted-by":"publisher","DOI":"10.1159\/000231075"},{"key":"S0031182000052173_ref007","first-page":"549","article-title":"Protective immunity to Nippostrongylus brasiliensis: the sequence of events which expels worms from the rat intestine","volume":"20","author":"Jones","year":"1971","journal-title":"Immunology"},{"key":"S0031182000052173_ref012","first-page":"637","article-title":"Two distinct populations of peripheral lymphocytes in mice distinguish able by immunofluorescence","volume":"19","author":"Raff","year":"1970","journal-title":"Immunology"},{"key":"S0031182000052173_ref004","doi-asserted-by":"publisher","DOI":"10.1159\/000231141"},{"key":"S0031182000052173_ref001","doi-asserted-by":"publisher","DOI":"10.1038\/2031039a0"},{"key":"S0031182000052173_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(73)90062-3"},{"key":"S0031182000052173_ref008","first-page":"767","article-title":"Protective immunity to Nippostrongylus brasiliensis in the rat: central role of the lymphocyte in worm expulsion","volume":"22","author":"Keller","year":"1972","journal-title":"Immunology"},{"key":"S0031182000052173_ref003","doi-asserted-by":"publisher","DOI":"10.1159\/000231097"},{"key":"S0031182000052173_ref016","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000072395"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000052173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T15:36:32Z","timestamp":1559144192000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000052173\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,6]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1975,6]]}},"alternative-id":["S0031182000052173"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000052173","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,6]]}}}