{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:10:02Z","timestamp":1739146202428,"version":"3.37.0"},"reference-count":34,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":9806,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1982,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The circadian migration of<jats:italic>Hymenolepis diminuta<\/jats:italic>in the small intestine of the rat may be correlated with a circadian variation in 5-hydroxytryptamine levels present in worm tissue, in the intestinal lumen, in the intestinal mucosa, with the amount of food present in the small intestine and in arterial blood. The 5-HT and food levels in uninfected animals were also determined. The 16.00 h stage in the circadian cycle marks both the commencement of host feeding, followed by rising 5-HT levels in both worm and host tissues, and initiation of an anteriad migration of worm biomass. It was found that 5-HT levels in the intestine of parasitized animals were significantly higher than in the intestine of uninfected controls. This is the first report of circadian variation in mucosal and luminal 5-HT levels. The similarity in the circadian patterns of worm migration and worm luminal, mucosal and blood 5-HT levels were striking. Fasting eliminated the circadian rise in intestinal 5-HT levels and the worms did not migrate. Luminal 5-HT levels were significantly lower in fasted animals than in the comparable rats fed<jats:italic>ad libitum<\/jats:italic>. When the intestine was ligatured at the pyloric sphincter, worm anteriad migration still occurred after feeding, indicating that the presence of exogenous food in the intestine is not a factor in the initial migration of the worms.<\/jats:p>","DOI":"10.1017\/s0031182000052732","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:39:28Z","timestamp":1244219968000},"page":"431-441","source":"Crossref","is-referenced-by-count":24,"title":["Circadian variation in the distribution of<i>Hymenolepis diminuta<\/i>(Cestoda) and 5-hydroxytryptamine levels in the gastro-intestinal tract of the laboratory rat"],"prefix":"10.1017","volume":"84","author":[{"given":"C. H","family":"Cho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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