{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T07:16:40Z","timestamp":1758266200552},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":8100,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1987,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Single percutaneous immunizations of Fischer rats with 1000 ultra-violet attenuated <jats:italic>Schistosoma japonicum<\/jats:italic> cercariae induced 52\u201388% resistance to challenge 4 weeks later. Increasing this to 3 immunizations induced 90% resistance to challenge, and this level of protection remained undiminished for up to 40 weeks after vaccination. Rats vaccinated with gamma-irradiated <jats:italic>S. mansoni<\/jats:italic> cercariae were resistant to challenge with <jats:italic>S. mansoni<\/jats:italic> but not <jats:italic>S. japonicum<\/jats:italic>. Similarly rats vaccinated with u.v.-attenuated <jats:italic>S. japonicum<\/jats:italic> cercariae were not resistant to heterologous challenge. Thus irradiated vaccines are species-specific in both permissive and non-permissive hosts.<\/jats:p>","DOI":"10.1017\/s0031182000053440","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:16:38Z","timestamp":1244218598000},"page":"49-54","source":"Crossref","is-referenced-by-count":23,"title":["The induction of species-specific immunity against <i>Schistosoma japonicum<\/i> by exposure of rats to ultra-violet attenuated cercariae"],"prefix":"10.1017","volume":"94","author":[{"given":"N. A.","family":"Moloney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Webbe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Hinchcliffe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000053440_ref006","first-page":"403","article-title":"On the host specificity of Schistosoma japonicum","volume":"82","author":"Hs\u00fcn","year":"1963","journal-title":"Chinese Medical Journal"},{"key":"S0031182000053440_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000051015"},{"key":"S0031182000053440_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000056705"},{"key":"S0031182000053440_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000001347"},{"key":"S0031182000053440_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053300"},{"key":"S0031182000053440_ref007","first-page":"518","article-title":"Studies on host-specificity of Schistosoma japonicum. 2. A comparison of development of the worms in different laboratory mamalian hosts","volume":"4","author":"Ito","year":"1953","journal-title":"Nisshin lagaku"},{"key":"S0031182000053440_ref001","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000051003"},{"key":"S0031182000053440_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90295-X"},{"key":"S0031182000053440_ref011","doi-asserted-by":"publisher","DOI":"10.2307\/3280983"},{"key":"S0031182000053440_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-8749(77)80008-7"},{"key":"S0031182000053440_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(82)90274-7"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000053440","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:56:33Z","timestamp":1558486593000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000053440\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,2]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,2]]}},"alternative-id":["S0031182000053440"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000053440","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,2]]}}}