{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T19:56:59Z","timestamp":1693598219921},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":9745,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1982,8]]},"abstract":"SUMMARY<\/jats:title>In mice infected with the intestinal flagellates Giardia muris<\/jats:italic> or Spironucleus muris<\/jats:italic>, together with the blood parasites Babesia microti<\/jats:italic> or Plasmodium yoelii<\/jats:italic>, there is a temporary decrease of flagellate cyst output coincident with the peak of the blood parasite infections, followed by a rapid return to normal levels. This decrease in cyst output is correlated with decreased numbers of trophozoites in the small intestine. The effect on S. muris<\/jats:italic> is more marked than that on G. muris<\/jats:italic>. Neither blood parasites has any effect on the total duration of the flagellate infection and the flagellates do not affect the blood parasites. In mice infected with G. muris<\/jats:italic> or S. muris<\/jats:italic> and P. berghei<\/jats:italic> there is also a decrease in cyst output but this is less apparent than in infections with B. microti<\/jats:italic> or P. yoelii<\/jats:italic> because of the fatal nature of the P. berghei<\/jats:italic> infection. It is suggested that the decrease in cyst output is probably due to changes in the contents of the small intestine or to non-specific immunological factors rather than to specific immunological changes.<\/jats:p>","DOI":"10.1017\/s0031182000054184","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:38:30Z","timestamp":1244205510000},"page":"101-110","source":"Crossref","is-referenced-by-count":3,"title":["Interactions between the intestinal flagellates Giardia muris<\/i> and Spironucleus muris<\/i> and the blood parasites Babesia microti, Plasmodium yoelii<\/i> and Plasmodium berghei<\/i> in mice"],"prefix":"10.1017","volume":"85","author":[{"given":"Sara J.","family":"Brett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. E. G.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000054184_ref006","first-page":"95","volume-title":"Isotope and Radiation Research on Animal Diseases and their Vectors","author":"Cox","year":"1980"},{"key":"S0031182000054184_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000054172"},{"key":"S0031182000054184_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(76)90015-1"},{"key":"S0031182000054184_ref017","doi-asserted-by":"publisher","DOI":"10.1258\/002367776780956845"},{"key":"S0031182000054184_ref010","doi-asserted-by":"publisher","DOI":"10.1136\/gut.16.7.553"},{"key":"S0031182000054184_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S003118200004748X"},{"key":"S0031182000054184_ref016","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-59-3-383"},{"key":"S0031182000054184_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5320(72)90071-8"},{"key":"S0031182000054184_ref001","unstructured":"Brett S. J. (1981). The immunology of infection with intestinal flagellates Giardia muris and Spironucleus muris in laboratory mice. Ph.D. thesis. University of London."},{"key":"S0031182000054184_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)91386-7"},{"key":"S0031182000054184_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(82)90003-7"},{"key":"S0031182000054184_ref007","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-72-1-79"},{"key":"S0031182000054184_ref008","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-85-2-358"},{"key":"S0031182000054184_ref012","doi-asserted-by":"publisher","DOI":"10.1017\/S003118200006234X"},{"key":"S0031182000054184_ref013","first-page":"405","article-title":"Existence du flagell\u00e9 Giaria muris dans les tissus et organes des souris \u00e0 infestation spontan\u00e9e","volume":"30","author":"Radulescu","year":"1971","journal-title":"Archives Roumaines de Pathologie Experimentale et de Microbiologic"},{"key":"S0031182000054184_ref014","doi-asserted-by":"publisher","DOI":"10.1136\/gut.17.12.953"},{"key":"S0031182000054184_ref015","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0016-5085(76)80097-2","article-title":"Giardiasis in the mouse: an animal model","volume":"71","author":"Roberts-Thomson","year":"1976","journal-title":"Gastroenterology"},{"key":"S0031182000054184_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(80)90047-4"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000054184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T16:50:36Z","timestamp":1558716636000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000054184\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,8]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1982,8]]}},"alternative-id":["S0031182000054184"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000054184","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,8]]}}}