{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T09:03:37Z","timestamp":1774343017492,"version":"3.50.1"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":9075,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1984,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The effects of the direction of gut flow, of injections of glucose and saline into different regions of the small intestine and of surgical re-routing or ligature of gastric, biliary and pancreatic secretions into the small intestine have been correlated with changes in the migratory response of the rat tapeworm <jats:italic>Hymenolepis diminuta<\/jats:italic>. Reversing the normal anterior to distal flow of luminal contents in the small intestine did not affect worm migration following feeding. Injections of a glucose-saline solution into the duodenum did not initiate a migratory response; similar injections into the mid- and posterior regions of the small intestine resulted in migrational responses similar to those following intragastric glucose feeding. Re-routing gastric secretions to the distal duodenum inhibited anterior migration of the worms beyond the new point of entry of gastric juices. Results following re-routing and ligation of the biliary and pancreatic secretions suggest that there is a potent cue to anteriad migration in the pancreatic secretions. Biliary secretions also appear to contain an additional migratory cue to worm migration. In order of importance the factors stimulating\/inhibiting worm migration are pancreatic &gt; gastric &gt; biliary &gt; glucose. The results support the hypothesis that the factors affecting worm distribution in the small intestine are interactive and synergistic, involve other luminal factors, such as 5- hydroxytryptamine and the physico-chemical gradients, and are of a regional nature such that the migratory response of a particular worm is directly related to its position in the small intestine when the cues to relocation are received.<\/jats:p>","DOI":"10.1017\/s003118200005469x","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T12:28:30Z","timestamp":1244204910000},"page":"421-430","source":"Crossref","is-referenced-by-count":13,"title":["Migrational responses of <i>Hymenolepis diminuta<\/i> to surgical alteration of gastro-intestinal secretions"],"prefix":"10.1017","volume":"88","author":[{"given":"M. V. K.","family":"Sukhdeo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. F.","family":"Mettrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S003118200005469X_ref016","doi-asserted-by":"publisher","DOI":"10.1139\/z82-109"},{"key":"S003118200005469X_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(77)90147-3"},{"key":"S003118200005469X_ref014","first-page":"85","volume-title":"Cues which influence Behaviour of Parasites","author":"Mettrick","year":"1982"},{"key":"S003118200005469X_ref024","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(83)80040-X"},{"key":"S003118200005469X_ref012","first-page":"70","article-title":"Competition for ingested nutrients between the tapeworm Hymenolepis diminuta and the rat host","volume":"64","author":"Mettrick","year":"1973","journal-title":"Canadian Journal of Public Health"},{"key":"S003118200005469X_ref019","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(81)90020-7"},{"key":"S003118200005469X_ref017","first-page":"183","volume-title":"Advances in Parasitology","volume":"12","author":"Mettrick","year":"1974"},{"key":"S003118200005469X_ref011","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00023415"},{"key":"S003118200005469X_ref021","doi-asserted-by":"publisher","DOI":"10.1139\/y83-020"},{"key":"S003118200005469X_ref010","doi-asserted-by":"publisher","DOI":"10.1139\/z71-221"},{"key":"S003118200005469X_ref009","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053798"},{"key":"S003118200005469X_ref001","volume-title":"Introduction to Probability and Statistics","author":"Alder","year":"1972"},{"key":"S003118200005469X_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-058980-7.50016-6"},{"key":"S003118200005469X_ref007","volume-title":"Statistics: Probability, Inference and Decision","author":"Hays","year":"1971"},{"key":"S003118200005469X_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000078094"},{"key":"S003118200005469X_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-058980-7.50009-9"},{"key":"S003118200005469X_ref015","doi-asserted-by":"publisher","DOI":"10.2307\/3280561"},{"key":"S003118200005469X_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(82)90010-8"},{"key":"S003118200005469X_ref023","first-page":"166","volume-title":"Cues which Influence Behaviour of Parasites","author":"Roberts","year":"1982"},{"key":"S003118200005469X_ref022","doi-asserted-by":"publisher","DOI":"10.2307\/3277301"},{"key":"S003118200005469X_ref003","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000052732"},{"key":"S003118200005469X_ref004","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-185X.1973.tb01114.x"},{"key":"S003118200005469X_ref020","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(77)90087-X"},{"key":"S003118200005469X_ref005","doi-asserted-by":"publisher","DOI":"10.1021\/ac60052a025"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S003118200005469X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T16:50:31Z","timestamp":1558630231000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S003118200005469X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,6]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1984,6]]}},"alternative-id":["S003118200005469X"],"URL":"https:\/\/doi.org\/10.1017\/s003118200005469x","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,6]]}}}