{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T19:58:55Z","timestamp":1693598335767},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":9623,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1982,12]]},"abstract":"<jats:p>A total of 120 young cotton rats were fed<jats:italic>ad libitum<\/jats:italic>for 10 weeks on either synthetic diets containing 2\u00b75, 5, 10 or 15% casein or on a stock breeding diet containing 20% crude protein. Half of the animals in each group were infected with the filarial nematode<jats:italic>Litomosoides carinii<\/jats:italic>and the food intake and body weight of each animal was measured. There was a trend towards increased food consumption in protein-deficient cotton rats and this was increased further in infected animals; however, differences between groups were not significant. Low protein diets reduced the rate of growth of uninfected and infected cotton rats; filarial infection intensified these adverse effects of under-nutrition and increased the number of rats which died in the lowest protein group. Protein deficiency had little effect on the number of<jats:italic>L. carinii<\/jats:italic>which developed, although fewer parasites became established in cotton rats fed on a 2\u00b75% diet than in those fed on a 10% diet. Parasites developing in protein-deficient animals were shorter than those developing in well-fed ones and embryo-genesis was retarded in female worms from protein-deficient animals. The onset of patency was retarded in protein-deficient animals and the microfilaraemia which developed subsequently was lower up to 120 days post-infection.<\/jats:p>","DOI":"10.1017\/s0031182000056328","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:36:28Z","timestamp":1244219788000},"page":"543-558","source":"Crossref","is-referenced-by-count":8,"title":["The host\u2013parasite relationships in normal and protein-malnourished cotton rats infected with<i>Litomosoides carinii<\/i>(Nematoda: Filarioidea)"],"prefix":"10.1017","volume":"85","author":[{"given":"D. M.","family":"Storey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000056328_ref030","first-page":"21","article-title":"Protein deficiency and cotton rat filariasis","volume":"65","author":"Storey","year":"1971","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"S0031182000056328_ref029","doi-asserted-by":"crossref","unstructured":"Storey D. M. (1982). Vitamin A deficiency and the development of Litomosoides carinii (Nematoda, Filarioidea) in cotton rats. Zeitschrift f\u00fcr Parasitenkunde (in the Press).","DOI":"10.1007\/BF00927666"},{"key":"S0031182000056328_ref016","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1976.11687126"},{"key":"S0031182000056328_ref010","doi-asserted-by":"publisher","DOI":"10.2307\/3274636"},{"key":"S0031182000056328_ref024","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(80)90017-X"},{"key":"S0031182000056328_ref006","first-page":"31","article-title":"Parasitic infection and host nutrition. Third European Multicolloquium of Parasitology","volume":"82","author":"Crompton","year":"1981","journal-title":"Parasitology"},{"key":"S0031182000056328_ref021","unstructured":"Orraca-Tetteh F. (1964). Protein values of Ghanaian diets and the effect on protein metabolism of infestation of the rat with Nippostrongylus muris. Ph.D. thesis, University of London."},{"key":"S0031182000056328_ref003","first-page":"4","article-title":"Effect of chronic roundworm infection (Toxocara canis) on protein metabolism in dogs fed diets of different protein value","volume":"23","author":"Al-Rabii","year":"1964","journal-title":"Proceedings of the Nutrition Society"},{"key":"S0031182000056328_ref028","first-page":"35","article-title":"Parasitic infection and host nutrition. 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Ph.D. thesis, University of Salford."},{"key":"S0031182000056328_ref007","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000041834"},{"key":"S0031182000056328_ref008","first-page":"1086","article-title":"Experimental bilharziasis in animals. VII. 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