{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T08:43:01Z","timestamp":1648975381054},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":7919,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1987,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Adult males and females of<jats:italic>Onchocerca gutturosa<\/jats:italic>were implanted into the peritoneal cavity of mice, and their survival was determined at intervals thereafter by post-mortem examination. Ten of 17 animals receiving males dissected free of bovine host tissues contained live parasites at necropsy up to 4 months later. Female worms digested free from connective tissue by collagenase did not survive well, even though they appeared motile and intact before implantation; only 2 were alive 10 days later in 2 of 16 recipients. When males and females still contained within connective tissue capsules were implanted they survived for up to 2 months, and microfilariae were detected transiently in the skin of 2 recipient mice. The results suggest the feasibility of maintaining adult<jats:italic>O. gutturosa<\/jats:italic>in rodents by this means, provided exposure of worms to enzymes used to free them from host tissue is avoided.<\/jats:p>","DOI":"10.1017\/s0031182000057620","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:14:53Z","timestamp":1244218493000},"page":"155-158","source":"Crossref","is-referenced-by-count":2,"title":["Implantation of adult Onchocerca gutturosa into laboratory rodents"],"prefix":"10.1017","volume":"95","author":[{"given":"K. A. El","family":"Sinnary","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"Bianco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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