{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:29:00Z","timestamp":1762100940643},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":7066,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1989,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The pulmonary and portal vasculature of na\u00efve mice of the 129\/Ola and CBA\/Ca strains has been studied by means of the vasculature casting technique. This involves injection of pigmented vinylite resin into the arterial and venous systems, followed by digestion of the tissues with KOH. The peripheral vessels of the arterial and portal systems of CBA\/Ca mice were numerous and highly branched. In contrast, casts prepared from 70\u201380% of na\u00efve 129\/Ola mice showed dramatic reductions in the number and extent of the peripheral vessels. In addition, such vessels appeared severely truncated. The remaining 20\u201330% of na\u00efve 129\/Ola mice yielded lung and liver casts that were indistinguishable from the CBA\/Ca casts. Casts prepared from 129\/Ola mice infected 6 weeks previously with<jats:italic>Schistosoma mansoni<\/jats:italic>cercariae showed the same segregation; faecal smears, together with observations of presence or absence of gross pathology in such mice confirmed that the vascular changes correlated with the \u2018non-permissive trait\u2019. We propose that such alterations facilitate the reportedly abnormal migration of schistosomes from the liver to the lungs in \u2018non-permissive\u2019 129\/Ola mice.<\/jats:p>","DOI":"10.1017\/s0031182000059096","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T14:45:46Z","timestamp":1244213146000},"page":"377-381","source":"Crossref","is-referenced-by-count":15,"title":["<i>Schistosoma mansoni<\/i>: evidence that vascular abnormalities correlate with the \u2018non- permissive\u2019 trait in 129\/Ola mice"],"prefix":"10.1017","volume":"99","author":[{"given":"A. A. F.","family":"Elsaghier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. J.","family":"Mclaren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000059096_ref021","first-page":"115","volume-title":"The Biology of Schistosomes: From Genes to Latrines","author":"Wilson","year":"1987"},{"key":"S0031182000059096_ref015","first-page":"527","volume-title":"Immunology of Parasitic Infections","author":"Smithers","year":"1982"},{"key":"S0031182000059096_ref007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1984.tb00784.x"},{"key":"S0031182000059096_ref020","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(68)91895-3"},{"key":"S0031182000059096_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(69)80464-6"},{"key":"S0031182000059096_ref001","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1987.56"},{"key":"S0031182000059096_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)91718-1"},{"key":"S0031182000059096_ref002","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1981.30.806"},{"key":"S0031182000059096_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000059084"},{"key":"S0031182000059096_ref008","doi-asserted-by":"publisher","DOI":"10.2307\/3281382"},{"key":"S0031182000059096_ref009","doi-asserted-by":"publisher","DOI":"10.1007\/BF00499100"},{"key":"S0031182000059096_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/BF00554527"},{"key":"S0031182000059096_ref017","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000086248"},{"key":"S0031182000059096_ref011","doi-asserted-by":"publisher","DOI":"10.1007\/BF01935985"},{"key":"S0031182000059096_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(89)90185-3"},{"key":"S0031182000059096_ref013","unstructured":"Rogers M. V. (1986). Schistosoma mansoni: studies of antigen recognition and immune expression inchronically infected and vaccinated guinea pigs. Ph.D. thesis, Brunei University, Uxbridge, Middlesex, U.K."},{"key":"S0031182000059096_ref014","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.22.8703"},{"key":"S0031182000059096_ref016","first-page":"12","article-title":"The mouse model of schistosome immunity","volume":"44","author":"Smithers","year":"1987","journal-title":"Acta Tropica"},{"key":"S0031182000059096_ref018","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1002\/j.1460-2075.1988.tb02834.x","article-title":"The glutathione transferase activity and tissue distribution of a cloned Mr 28 K protective antigen of Schistosoma mansoni","volume":"7","author":"Taylor","year":"1988","journal-title":"EMBO Journal"},{"key":"S0031182000059096_ref019","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1986.36"},{"key":"S0031182000059096_ref023","doi-asserted-by":"publisher","DOI":"10.2307\/3282180"},{"key":"S0031182000059096_ref022","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1128\/IAI.56.11.2948-2952.1988","article-title":"Schistosoma mansoni antigens differentially recognised by resistant WEHI 129\/J mice","volume":"56","author":"Wright","year":"1988","journal-title":"Infection and Immunity"},{"key":"S0031182000059096_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(68)91896-5"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000059096","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T06:49:54Z","timestamp":1589870994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000059096\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,12]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1989,12]]}},"alternative-id":["S0031182000059096"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000059096","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,12]]}}}