{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:24:06Z","timestamp":1770510246554,"version":"3.49.0"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":6458,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1991,8]]},"abstract":"<jats:p>This paper describes patterns of infection with <jats:italic>Opisthorchis viverrini<\/jats:italic> within a human community assessed by egg count, parasite-specific antibody levels and worm burden determined by expulsion chemotherapy. All three measurements increased significantly with age, reaching a plateau in young adults. There were no significant sex-associated differences in the prevalence or intensity of infection, antibody levels, or in the frequency of heavy worm burdens. A striking 81\u00b75% of the total <jats:italic>Opisthorchis<\/jats:italic> population and 74% of the total egg output were expelled by the most heavily infected 10% of the humans sampled. This extreme over-dispersion, together with recent findings that hepatobiliary disease frequently accompanies heavy infections, argues that the priority for community-based parasite control programmes should be to maximize treatment and health promotion efforts toward heavily infected individuals.<\/jats:p>","DOI":"10.1017\/s0031182000059333","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T14:28:26Z","timestamp":1244212106000},"page":"97-101","source":"Crossref","is-referenced-by-count":42,"title":["Distribution patterns of <i>Opisthorchis viverrini<\/i> within a human community"],"prefix":"10.1017","volume":"103","author":[{"given":"M. R.","family":"Haswell-Elkins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. B.","family":"Elkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paiboon","family":"Sithithaworn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phattara","family":"Treesarawat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sasithorn","family":"Kaewkes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000059333_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(90)90159-C"},{"key":"S0031182000059333_ref017","first-page":"138","article-title":"Opisthorchis viverrini: intensity and rates of infection in cyprinoid fish from an endemic focus in northeast Thailand","volume":"13","author":"Vichasri","year":"1982","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000059333_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)90591-R"},{"key":"S0031182000059333_ref001","first-page":"413","article-title":"Studies on the chemotherapy of human opisthorchiasis \u2013 III. 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