{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T09:37:14Z","timestamp":1758274634278},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":6336,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:p>Infectivity of<jats:italic>Trichinella pseudospiralis<\/jats:italic>in Chinese hamsters was greater than that of<jats:italic>Trichinella spiralis<\/jats:italic>. Concurrent infection with these two species of parasite was accompanied by an increase in infectivity of<jats:italic>T. spiralis<\/jats:italic>. The infectivity of<jats:italic>T. pseudospiralis<\/jats:italic>, but not that of<jats:italic>T. spiralis<\/jats:italic>, was significantly influenced by host age. Regardless of host age,<jats:italic>T. pseudospiralis<\/jats:italic>was more infective for the Chinese hamster than was<jats:italic>T. spiralis<\/jats:italic>. Early during infection, enteritis (myeloperoxidase activity) in hamsters infected with<jats:italic>T. pseudospiralis<\/jats:italic>alone was significantly less than that seen in animals infected with<jats:italic>T. spiralis<\/jats:italic>alone or with both species concurrently. Myositis in hamsters infected with<jats:italic>T. pseudospiralis<\/jats:italic>alone was significantly less on days 14, 17 and 25 post-infection (p.i.) than that observed in concurrently infected or<jats:italic>T. spiralis<\/jats:italic>-infected animals. On days 11 and 14 p.i. inflammation in diaphragm muscle from concurrently infected hamsters was significantly less than that seen in animals infected with<jats:italic>T. spiralis<\/jats:italic>alone. Muscle histology supported these chemical data on myositis. Suppression of the host inflammatory response against early muscle-stage larvae of<jats:italic>T. pseudospiralis<\/jats:italic>underlies the greater infectivity of this parasite for the Chinese hamster.<\/jats:p>","DOI":"10.1017\/s0031182000059989","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T14:25:32Z","timestamp":1244211932000},"page":"465-470","source":"Crossref","is-referenced-by-count":7,"title":["<i>Trichinella pseudospiralis<\/i>overcomes innate resistance of the chinese hamster to<i>Trichinella spiralis<\/i>"],"prefix":"10.1017","volume":"103","author":[{"given":"E.","family":"Larsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. L.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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