{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T22:05:38Z","timestamp":1648764338301},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":6274,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The localization of adult <jats:italic>Schistosoma mansoni<\/jats:italic> originating from Guadeloupe (West Indies) was analysed in the natural host <jats:italic>Rattus rattus<\/jats:italic> in experimental and natural infections. A transfer of schistosomes from the porto-mesenteric system to the lungs occurs between the 4th and the 20th weeks post-infection, with a peak between 4 and 8 weeks; it should be noted that the worms start laying eggs at 4 weeks post-infection. In both experimentally and naturally infected <jats:italic>R. rattus<\/jats:italic> the relocation of schistosomes in the lungs is correlated with the total worm burden. Between 6 and 12 weeks post-infection some adult worms and numerous eggs are trapped in the liver. A high mortality in the worm population coincides with the migration of the parasites from the porto-mesenteric veins to the lungs. In re-infected <jats:italic>R. rattus<\/jats:italic> a relationship appears between the presence of schistosomes in the lungs and resistance to reinfection. It is concluded that, as already postulated previously in mice, resistance to re-infection in the natural host <jats:italic>R. rattus<\/jats:italic> is at least partly correlated with the hepatic pathology caused by the schistosomes of the primary infection.<\/jats:p>","DOI":"10.1017\/s0031182000060790","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T10:26:48Z","timestamp":1244197608000},"page":"51-57","source":"Crossref","is-referenced-by-count":6,"title":["Relocation of <i>Schistosoma mansoni<\/i> in the lungs and resistance to reinfection in <i>Rattus rattus<\/i>"],"prefix":"10.1017","volume":"104","author":[{"given":"D.","family":"Imbert-Establet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Combes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000060790_ref012","unstructured":"Wilson R. A. (1980). Is immunity to Schistosoma mansoni in the chronically infected laboratory mouse an artefact of pathology? Proceedings of the Third European Multicolloquium of Parasitology, p 37."},{"key":"S0031182000060790_ref003","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000059084"},{"key":"S0031182000060790_ref001","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000059102"},{"key":"S0031182000060790_ref008","first-page":"41","article-title":"Etude exp\u00e9rimentale de la permissivit\u00e9 du rat sauvage (Rattus rattus) de Guadeloupe \u00e0 l'\u00e9gard de Schistosoma mansoni. Hypoth\u00e8ses sur le r\u00f4le de cet h\u00f4te dans la dynamique des foyers naturels","volume":"37","author":"Jourdane","year":"1980","journal-title":"Acta Tropica"},{"key":"S0031182000060790_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60434-0"},{"key":"S0031182000060790_ref009","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000086248"},{"key":"S0031182000060790_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(90)90414-Y"},{"key":"S0031182000060790_ref007","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/1982576573"},{"key":"S0031182000060790_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000059096"},{"key":"S0031182000060790_ref011","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/1978532223"},{"key":"S0031182000060790_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000051696"},{"key":"S0031182000060790_ref005","doi-asserted-by":"publisher","DOI":"10.2307\/3278393"},{"key":"S0031182000060790_ref002","doi-asserted-by":"publisher","DOI":"10.1038\/345018a0"},{"key":"S0031182000060790_ref014","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1983.tb00776.x"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000060790","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T18:37:03Z","timestamp":1558031823000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000060790\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["S0031182000060790"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000060790","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}