{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:47:10Z","timestamp":1777693630782,"version":"3.51.4"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":6214,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1992,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>This study examines the persistence of predisposition to <jats:italic>Ascaris lumbricoides<\/jats:italic> and <jats:italic>Trichuris trichiura<\/jats:italic> during repeated chemotherapy in an urban community in Kuala Lumpur, Malaysia. Significant predisposition was observed over 2 periods of reinfection with and without age-standardization of data. Analysis of different age groups indicated that predisposition was most strongly detectable in the younger age classes. The intensities of infection with both parasites were strongly correlated at each cycle of intervention, suggesting that individuals were similarly predisposed to both species.<\/jats:p>","DOI":"10.1017\/s0031182000061837","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T10:25:25Z","timestamp":1244197525000},"page":"371-377","source":"Crossref","is-referenced-by-count":15,"title":["The effect of repeated chemotherapy on age-related predisposition to <i>Ascaris lumbricoides<\/i> and <i>Trichuris trichiura<\/i>"],"prefix":"10.1017","volume":"104","author":[{"given":"L.","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. P.","family":"Kan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. A. P.","family":"Bundy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000061837_ref025","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(88)90159-9"},{"key":"S0031182000061837_ref024","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/0035-9203(87)90306-3","article-title":"Reinfection of people with Ascaris lumbricoides following single, 6-month and 12-month interval mass chemotherapy in Okpo village, rural Burma","volume":"81","author":"Thein","year":"1987","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"S0031182000061837_ref023","volume-title":"Ecological Methods with Particular Reference to the Study of Insect Populations","author":"Southwood","year":"1978"},{"key":"S0031182000061837_ref022","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000058856"},{"key":"S0031182000061837_ref017","first-page":"180","article-title":"Soil-transmitted helminthiasis in Selangor, Malaysia","volume":"37","author":"Kan","year":"1982","journal-title":"Medical Journal of Malaysia"},{"key":"S0031182000061837_ref016","doi-asserted-by":"publisher","DOI":"10.1017\/S003118200005873X"},{"key":"S0031182000061837_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(90)90284-L"},{"key":"S0031182000061837_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(86)90384-6"},{"key":"S0031182000061837_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(82)90272-3"},{"key":"S0031182000061837_ref010","volume-title":"Medical Laboratory Manual For Tropical Countries","volume":"1","author":"Cheesbrough","year":"1987"},{"key":"S0031182000061837_ref015","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000057772"},{"key":"S0031182000061837_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(85)90178-6"},{"key":"S0031182000061837_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800061719"},{"key":"S0031182000061837_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(87)90442-1"},{"key":"S0031182000061837_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000052288"},{"key":"S0031182000061837_ref001","doi-asserted-by":"publisher","DOI":"10.1038\/297557a0"},{"key":"S0031182000061837_ref009","unstructured":"Chan L. 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