{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:52:50Z","timestamp":1777499570723,"version":"3.51.4"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":6580,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1991,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Three techniques for estimating the intensity of <jats:italic>Opisthorchis viverrini<\/jats:italic> infection in individuals from a Northeast That community are compared. Egg counts were determined using a quantitative formalin\/ethyl acetate technique, worm burdens were estimated by expulsion chemotherapy and antibody levels were measured by ELISA. Log-transformed worm and egg counts were closely correlated (<jats:italic>r<\/jats:italic> = 0\u00b780), suggesting that both measurements provide good assessments of relative intensity of infection. However, no <jats:italic>Opisthorchis<\/jats:italic> worms were recovered from 34 people with high egg counts; probably due to problems with the expulsion technique in some individuals. Examination of egg production per fluke indicated that each fluke contributed an average of 180 eggs per gram (epg) of faeces and fecundity was negatively associated with total worm burden. Serum IgG levels correlated significantly with <jats:italic>Opisthorchis<\/jats:italic> egg count (<jats:italic>r<\/jats:italic> = 0\u00b761) at two independent assessments. Although significant associations were observed between antibody levels and echinostome infection, analysis suggested that these reflected independent associations between these two variables and <jats:italic>Opisthorchis<\/jats:italic> infection and age. We conclude that all three measurements are useful for epidemiological studies.<\/jats:p>","DOI":"10.1017\/s0031182000062600","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T14:33:51Z","timestamp":1244212431000},"page":"283-288","source":"Crossref","is-referenced-by-count":92,"title":["<i>Opisthorchis viverrini<\/i>: relationships between egg counts, worms recovered and antibody levels within an endemic community in Northeast Thailand"],"prefix":"10.1017","volume":"102","author":[{"given":"D. B.","family":"Elkins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sithithaworn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Haswell-Elkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kaewkes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Awacharagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Wongratanacheewin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000062600_ref018","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1988.38.356"},{"key":"S0031182000062600_ref016","first-page":"234","article-title":"Enzyme-linked immunosorbent assay for detection of Opisthorchis viverrini infection","volume":"16","author":"Srivatanakul","year":"1985","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000062600_ref015","first-page":"215","article-title":"Hepatic carcinoma with opisthorchiasis","volume":"9","author":"Sonakul","year":"1978","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000062600_ref014","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000062594"},{"key":"S0031182000062600_ref011","first-page":"1119","article-title":"Public health aspects of opisthorchiasis in Thailand","volume":"34","author":"Preuksaraj","year":"1984","journal-title":"Drug Research"},{"key":"S0031182000062600_ref010","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1984.33.73"},{"key":"S0031182000062600_ref009","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/path.1700720130","article-title":"The relationship between primary carcinoma of the liver and infestation with Clonorchis sinensis","volume":"72","author":"Hou","year":"1956","journal-title":"Journal of Pathology and Bacteriology"},{"key":"S0031182000062600_ref008","first-page":"1167","article-title":"Opisthorchis viverrini infection: pathogenesis and clinical features","volume":"34","author":"Harinasuta","year":"1984","journal-title":"Drug Research"},{"key":"S0031182000062600_ref007","unstructured":"Hall A. (1981). Aspects of parasitic infection and host nutrition. Ph.D. thesis, University of Cambridge."},{"key":"S0031182000062600_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X0000657X"},{"key":"S0031182000062600_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90132-3"},{"key":"S0031182000062600_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(86)90384-6"},{"key":"S0031182000062600_ref001","first-page":"413","article-title":"Studies on the chemotherapy of human opisthorchiasis \u2013 III. Minimum effective dose of praziquantel","volume":"12","author":"Bunnag","year":"1981","journal-title":"South east Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000062600_ref012","first-page":"1215","article-title":"Worms recovered in stools following praziquantel treatment","volume":"34","author":"Radomyos","year":"1984","journal-title":"Drug Research"},{"key":"S0031182000062600_ref017","first-page":"451","article-title":"Relationship between prevalence and intensity of Opisthorchis viverrini infection, and clinical symptoms and signs in a rural community in northeast Thailand","volume":"62","author":"Upatham","year":"1984","journal-title":"Bulletin of the World Health Organization"},{"key":"S0031182000062600_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(89)90662-7"},{"key":"S0031182000062600_ref004","first-page":"8","article-title":"Serodiagnosis of Opisthorchis viverrini infestation by an enzyme immunoassay","volume":"33","author":"Feldheim","year":"1982","journal-title":"Tropenmedizin und Parasitologie"},{"key":"S0031182000062600_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(90)90159-C"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000062600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T22:05:18Z","timestamp":1558130718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000062600\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,4]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,4]]}},"alternative-id":["S0031182000062600"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000062600","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,4]]}}}