{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:10:26Z","timestamp":1790691026840,"version":"4.1.0"},"reference-count":34,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":8345,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1986,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Interactions between tapeworm species in a single host offer intriguing opportunities for immunological studies that attempt to identify the mechanism(s) underlying protection against cestode infections. Mice that are immunized against<jats:italic>Hymenolepis citelli<\/jats:italic>infections were shown to be refractory to subsequent<jats:italic>H. diminuta<\/jats:italic>challenge infections. The reciprocity of the response was also demonstrated, although the protection recorded for<jats:italic>H. diminuta<\/jats:italic>when mice are sensitized with<jats:italic>H. citelli<\/jats:italic>is weaker than that observed when mice are primed with<jats:italic>H. diminuta<\/jats:italic>against<jats:italic>H. citelli<\/jats:italic>challenge.<jats:italic>H. citelli<\/jats:italic>was also shown to be expelled simultaneously during the rejection phase of<jats:italic>H. diminuta<\/jats:italic>in concurrent infections, indicating the susceptibility of the former tapeworm to the rejection mechanism initiated by the latter.<jats:italic>H. microstoma<\/jats:italic>immunized mice were shown to be strongly protected against heterologous<jats:italic>H. citelli<\/jats:italic>challenge. However, mice primed against<jats:italic>H. citelli<\/jats:italic>were not as strongly protected against<jats:italic>H. microstoma<\/jats:italic>challenge infections: a statistically significant protection was obtained only after a 12-cysticercoid<jats:italic>H. citelli<\/jats:italic>primary infection, although a 6-cyst infection did stunt the growth of<jats:italic>H. microstoma<\/jats:italic>challenge worms. It is presently suggested that the cross-protective responses observed in the study between<jats:italic>H. citelli, H. diminuta<\/jats:italic>and<jats:italic>H. microstoma<\/jats:italic>may have emanated from a specific immunological cross-reactivity due to the sharing of similar immunogens.<\/jats:p>","DOI":"10.1017\/s0031182000065525","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T16:20:46Z","timestamp":1244218846000},"page":"665-674","source":"Crossref","is-referenced-by-count":7,"title":["Immunity to tapeworms: intraspecific cross-protective interactions between<i>Hymenolepis citelli, H. diminuta<\/i>and<i>H. microstoma<\/i>in mice"],"prefix":"10.1017","volume":"92","author":[{"given":"Sidi T. O.","family":"Alghali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. K.","family":"Grencis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000065525_ref004","first-page":"297","article-title":"Immunogenicity and phylogenetic relationship of tapeworm antigens produced by Hymenolepis nana and Hymenolepis diminuta","volume":"15","author":"Coleman","year":"1968","journal-title":"Immunology"},{"key":"S0031182000065525_ref022","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(75)90077-6"},{"key":"S0031182000065525_ref028","first-page":"571","volume-title":"Symposia of the British Society for Parasitology","volume":"21","author":"Parkhouse","year":"1984"},{"key":"S0031182000065525_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(77)90049-2"},{"key":"S0031182000065525_ref013","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053798"},{"key":"S0031182000065525_ref020","doi-asserted-by":"publisher","DOI":"10.2307\/3279166"},{"key":"S0031182000065525_ref023","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000044929"},{"key":"S0031182000065525_ref011","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1017\/S003118200005455X","article-title":"Interactions between Moniliformis (Acanthocephala) and Nippostrongylus (Nematoda) in the small intestine of laboratory rats","volume":"88","author":"Holland","year":"1984","journal-title":"Parasitology"},{"key":"S0031182000065525_ref014","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000047661"},{"key":"S0031182000065525_ref005","doi-asserted-by":"publisher","DOI":"10.1038\/273623a0"},{"key":"S0031182000065525_ref031","first-page":"107","volume-title":"Symposia of the British Society for Parasitology","volume":"18","author":"Urquhart","year":"1980"},{"key":"S0031182000065525_ref025","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000050952"},{"key":"S0031182000065525_ref024","doi-asserted-by":"publisher","DOI":"10.1007\/BF00928974"},{"key":"S0031182000065525_ref010","doi-asserted-by":"publisher","DOI":"10.1017\/S003118200004659X"},{"key":"S0031182000065525_ref018","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000050241"},{"key":"S0031182000065525_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(72)90010-0"},{"key":"S0031182000065525_ref016","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000049519"},{"key":"S0031182000065525_ref033","first-page":"301","volume-title":"Biology of Parasites","author":"Weinmann","year":"1966"},{"key":"S0031182000065525_ref030","volume-title":"Statistical Methods","author":"Snedecor","year":"1967"},{"key":"S0031182000065525_ref001","unstructured":"Alghali S. T. O. (1980). Intestinal immunity to tapeworms: the rejection of Hymenolepis citelli by mice and rats. Ph.D. thesis, University of Glasgow."},{"key":"S0031182000065525_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000053154"},{"key":"S0031182000065525_ref029","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(59)90006-2"},{"key":"S0031182000065525_ref003","unstructured":"Befus A. D. (1975 b). Intestinal immune responses of mice to the tapeworms Hymenolepis diminuta and H. microstoma. Ph.D thesis, University of Glasgow."},{"key":"S0031182000065525_ref007","unstructured":"Elowni E. E. (1980). Immunity to tapeworms: vaccination against Hymenolepis diminuta and role of the bursa of Fabricius in rejection of Raillietina cesticillus. Ph.D. thesis, University of Glasgow."},{"key":"S0031182000065525_ref009","unstructured":"Goodall R. I. (1973). Studies on the growth, location specificity and immunobiology of some hymenolepid tapeworms. Ph.D. thesis, University of Glasgow."},{"key":"S0031182000065525_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-058980-7.50015-4"},{"key":"S0031182000065525_ref015","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000045479"},{"key":"S0031182000065525_ref017","unstructured":"Howard R. J. (1976 b). Aspects of the host\/parasite relationship of Hymenolepis microstoma. Ph.D. thesis, University of Glasgow."},{"key":"S0031182000065525_ref019","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000046783"},{"key":"S0031182000065525_ref021","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000000512"},{"key":"S0031182000065525_ref026","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(79)90008-0"},{"key":"S0031182000065525_ref027","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(85)90070-0"},{"key":"S0031182000065525_ref034","doi-asserted-by":"publisher","DOI":"10.2307\/3280271"},{"key":"S0031182000065525_ref032","first-page":"37","article-title":"Immunity to T. spiralis in irradiated mice","volume":"9","author":"Wakelin","year":"1979","journal-title":"International Journal for Parasitology"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000065525","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T07:14:32Z","timestamp":1589872472000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000065525\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,6]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,6]]}},"alternative-id":["S0031182000065525"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000065525","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,6]]}}}