{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T12:08:28Z","timestamp":1764936508320},"reference-count":27,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":4905,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1995,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Seven cDN A clones of<jats:italic>Schistosoma mansoni<\/jats:italic>containing the C-terminal part of the deduced sequence of a mucin-like protein have been identified. The protein contains 28% threonines, 20% serines, and has a pi of 3middot;4. On Northern blots of RNA of adult worms, the cDNA clones detect 2 transcripts of 1middot;65 and 4middot;2 kb which are expressed only in female worms. The tissue of gene expression, as revealed by<jats:italic>in situ<\/jats:italic>hybridization, is the epithelium surrounding the female reproduction duct proximal to its entrance into the ootype. Accumulation of N-glycosylation sites suggests that the protein, like other mucins, might form a protective layer, coating the lining of the duct. Regarding its acidic pi, we hypothesize a role in preventing premature egg-shell formation. This is the first female-specifically transcribed sequence, hitherto known in<jats:italic>S<\/jats:italic>.<jats:italic>mansoni<\/jats:italic>that is not expressed in the vitellaria.<\/jats:p>","DOI":"10.1017\/s0031182000065987","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T13:40:57Z","timestamp":1244209257000},"page":"477-483","source":"Crossref","is-referenced-by-count":34,"title":["A female-specific cDNA sequence of<i>Schistosoma mansoni<\/i>encoding a mucin-like protein that is expressed in the epithelial cells of the reproductive duct"],"prefix":"10.1017","volume":"111","author":[{"given":"M.","family":"Menrath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Michel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000065987_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(88)90138-6"},{"key":"S0031182000065987_ref026","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(91)90101-2"},{"key":"S0031182000065987_ref024","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.8.1954"},{"key":"S0031182000065987_ref014","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761995000200010"},{"key":"S0031182000065987_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90612-G"},{"key":"S0031182000065987_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/0735-0651(90)90042-E"},{"key":"S0031182000065987_ref001","doi-asserted-by":"publisher","DOI":"10.2307\/3276242"},{"key":"S0031182000065987_ref025","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115360"},{"key":"S0031182000065987_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(91)90263-N"},{"key":"S0031182000065987_ref011","doi-asserted-by":"crossref","first-page":"7686","DOI":"10.1016\/S0021-9258(18)68553-9","article-title":"A new repetitive protein from Xenopus laevis skin highly homologous to pancreatic spasmolytic polypeptide","volume":"263","author":"Hoffmann","year":"1988","journal-title":"Journal of Biological Chemistry"},{"key":"S0031182000065987_ref005","doi-asserted-by":"publisher","DOI":"10.2307\/3280487"},{"key":"S0031182000065987_ref007","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1967.16.483"},{"key":"S0031182000065987_ref003","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.15.5544"},{"key":"S0031182000065987_ref002","doi-asserted-by":"publisher","DOI":"10.2307\/3279544"},{"key":"S0031182000065987_ref004","doi-asserted-by":"publisher","DOI":"10.1021\/bi00591a005"},{"key":"S0031182000065987_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(92)90221-5"},{"key":"S0031182000065987_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(94)90141-4"},{"key":"S0031182000065987_ref009","first-page":"18","article-title":"Schistosomiasis Studien","volume":"6","author":"G\u00f6nnert","year":"1955","journal-title":"Zeitschrift f\u00fcr Tropenmedizin"},{"key":"S0031182000065987_ref010","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.1016\/S0021-9258(18)83373-7","article-title":"Molecular cloning of human intestinal mucin cDNAs. 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