{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:38:22Z","timestamp":1759991902459},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":16046,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1965,5]]},"abstract":"<jats:p>The results are described of a study of the distribution of the antigens in <jats:italic>F. hepatica<\/jats:italic> at various stages of development, and in the liver and spleen of experimentally infected rats using globulins labelled with fluorescein isothiocyanate, from rats and sheep infected with <jats:italic>F. hepatica<\/jats:italic>.<\/jats:p><jats:p>Possible uses of this technique in aiding the diagnosis of fascioliasis are indicated.<\/jats:p><jats:p>I wish to thank Dr A. W. J. Broome for a supply of the metacercariae of <jats:italic>F. hepatica<\/jats:italic>, and Dr J. S. S. Lowe who kindly isolated and labelled the globulins with fluorescein isothiocyanate. Miss Enid Eccleston gave valuable technical assistance.<\/jats:p>","DOI":"10.1017\/s0031182000068700","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T13:27:30Z","timestamp":1244208450000},"page":"209-214","source":"Crossref","is-referenced-by-count":15,"title":["An immunocytochemical study with <i>Fasciola hepatica<\/i>"],"prefix":"10.1017","volume":"55","author":[{"given":"E.","family":"Thorpe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000068700_ref003","first-page":"951","article-title":"L'evolution compar\u00e9e du proteinogramme et de la r\u00e9action de fixation du complement dans l'immunisation exp\u00e9rimentale du lapin avec des antig\u00e8nes parasitaires","volume":"252","author":"Benex","year":"1961","journal-title":"C. r. hebd. S\u00e9anc. Acad. 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Parasit."},{"key":"S0031182000068700_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(61)90014-5"},{"key":"S0031182000068700_ref006","doi-asserted-by":"publisher","DOI":"10.1042\/bj0341248"},{"key":"S0031182000068700_ref012","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/94.2.126"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000068700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T15:41:55Z","timestamp":1559576515000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000068700\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1965,5]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1965,5]]}},"alternative-id":["S0031182000068700"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000068700","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1965,5]]}}}