{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T16:36:56Z","timestamp":1648831016526},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":14674,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1969,2]]},"abstract":"<jats:p>Red blood cells from rats were labelled with <jats:sup>51<\/jats:sup>Cr by <jats:italic>in vitro<\/jats:italic> incubation with labelled sodium chromate. After re-injection of autologous labelled red cells, rats, each infected with 5000 <jats:italic>N. brasiliensis<\/jats:italic> larvae, and non-infected controls were placed in individual metabolism cages. Twenty-four hour samples of faeces and urine from both groups were collected throughout the course of the infection. From a knowledge of the specific radioactivity of host blood, it was possible to express the radioactivity found in the faeces and urine in terms of volume of whole blood. A burden of approximately 1000 adult worms caused a blood loss of about 100 \u03bcl every 24 h during the period day 4 to day 14 after infection. This gastro-intestinal haemorrhage could provide a vehicle whereby antibody gains access to the worm. No radioactivity was found in adult worms isolated from infected rats killed at 2-day intervals throughout the course of the infection. Adult <jats:italic>N. brasiliensis<\/jats:italic> did not ingest an appreciable quantity of host blood.<\/jats:p>","DOI":"10.1017\/s0031182000069870","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T17:15:58Z","timestamp":1244222158000},"page":"123-127","source":"Crossref","is-referenced-by-count":4,"title":["Radio isotope studies on the blood loss associated with <i>Nippostrongylus brasiliensis<\/i> infection in rats"],"prefix":"10.1017","volume":"59","author":[{"given":"J. T. McL.","family":"Neilson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000069870_ref010","first-page":"238","article-title":"Radiochromium-labelled erythrocytes for the detection of gastrointestinal hemorrhage","volume":"44","author":"Owen","year":"1954","journal-title":"J. Lab. clin. 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