{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:39:05Z","timestamp":1758634745699},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":13885,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1971,4]]},"abstract":"<jats:p>Isoenzyme patterns of normal adult<jats:italic>Nippostrongylus brasiliensis<\/jats:italic>were compared with those of damaged worms permanently affected by immunity and adapted worms which show increased resistance to immunity.<\/jats:p><jats:p>Isoenzymes of acetylcholinesterase, found in glands of the head end of the worms, showed changes in damaged and adapted worms which can be related to the effects of immunity.<\/jats:p><jats:p>Aminopeptidases and non-specific esterases from the same glands were unchanged in worms affected by immunity.<\/jats:p><jats:p>Isoenzymes of acid phosphatase found in the gut of the worms were altered in damaged and adapted worms; these changes are probably secondary to the changes in acetylcholinesterases.<\/jats:p><jats:p>Of the enzymes studied, acetylcholinesterase is the enzyme most likely to be the antigen which stimulates host immunity, but final proof of this is required.<\/jats:p><jats:p>We are most grateful to Dr Valerie E. Jones for many helpful suggestions.<\/jats:p>","DOI":"10.1017\/s0031182000071572","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T17:10:56Z","timestamp":1244221856000},"page":"339-347","source":"Crossref","is-referenced-by-count":74,"title":["The effect of immunity upon some enzymes of the parasitic nematode,<i>Nippostrongylus brasiliensis<\/i>"],"prefix":"10.1017","volume":"62","author":[{"given":"A. J.","family":"Edwards","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"Burt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridget M.","family":"Ogilvie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000071572_ref018","volume-title":"Chromatographic and Electrophoretic Techniques","volume":"2","author":"Shaw","year":"1968"},{"key":"S0031182000071572_ref015","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(64)90035-9"},{"key":"S0031182000071572_ref005","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/genetics\/52.6.1345","article-title":"Genetic variation in red cell esterases of rabbits","volume":"52","author":"Grunder","year":"1965","journal-title":"Genetics"},{"key":"S0031182000071572_ref001","volume-title":"Chromatographic and Electrophoretic Techniques","volume":"2","author":"Akroyd","year":"1968"},{"key":"S0031182000071572_ref011","first-page":"31","article-title":"Immunity to Nippostrongylus brasiliensis","volume":"7","author":"Ogilvie","year":"1969","journal-title":"Symposia of the British Society for Parasitology"},{"key":"S0031182000071572_ref004","doi-asserted-by":"publisher","DOI":"10.3109\/10520295009110962"},{"key":"S0031182000071572_ref006","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1954.0015"},{"key":"S0031182000071572_ref008","article-title":"Protective immunity to Nippostrongylus brasiliensis: the sequence of events which expels worms from the rat intestine","author":"Jones","year":"1971","journal-title":"Immunology"},{"key":"S0031182000071572_ref017","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/62.3.337"},{"key":"S0031182000071572_ref002","unstructured":"Burt J. 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