{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:00:33Z","timestamp":1791892833201,"version":"4.3.4"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":5849,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1993,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>A control programme of opisthorchiasis was carried out for three years in three villages of northeast Thailand in order to compare the effectiveness of two intervention measures. The intervention measures employed were to give praziquantel treatment to all infected people either once (village I) or twice (village II) per year with the integration of regular health education and sanitation improvement. A control village (village III) received no intervention during the study. Sampling of the population in these villages to estimate prevalence, intensity, reinfection and incidence of infection as well as knowledge of opisthorchiasis and number of latrines was performed at 6 monthly intervals throughout the duration of the study. At the initial assessment, there were no significant differences in the prevalence and intensity of infection of villages I and II. Both values were greatly reduced when assessed 6 months after the initiation of treatment, and the decrease in prevalence and intensity of infection did not differ between villages I and II. The control village (village III), during the first 2 years, exhibited slight variation in the prevalence and intensity, and these decreased considerably in the third year of the study. The reinfection rate per 6 months in villages I and II was nearly equal. The incidence rate per 6 months in the two treated villages was lower than that of the control village. Marked improvement in knowledge of opisthorchiasis, behavioural changes of eating raw fish and increased numbers of latrines was evident in all of the villages during this study. The study showed that the effectiveness of annual drug treatment is similar to that of 6 monthly treatments when combined with regular health education and sanitation improvement.<\/jats:p>","DOI":"10.1017\/s0031182000075107","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T10:12:16Z","timestamp":1244196736000},"page":"283-288","source":"Crossref","is-referenced-by-count":25,"title":["Field trials in the control of\n                    <i>Opisthorchis viverrini<\/i>\n                    with an integrated programme in endemic areas of northeast Thailand"],"prefix":"10.1017","volume":"106","author":[{"given":"S.","family":"Saowakontha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Pipitgool","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Pariyanonda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tesana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Rojsathaporn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Intarakhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000075107_ref015","first-page":"609","article-title":"Mass treatment of opisthorchiasis in Northeast Thailand","volume":"13","author":"Vivatanasesth","year":"1982","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000075107_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(88)90099-9"},{"key":"S0031182000075107_ref013","first-page":"451","article-title":"Relationship between prevalence and intensity of Opisthorchis viverrini infection, and clinical symptoms and signs in a rural community in Northeast Thailand","volume":"62","author":"Upatham","year":"1984","journal-title":"Bulletin of the World Health Organization"},{"key":"S0031182000075107_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(90)90159-C"},{"key":"S0031182000075107_ref007","first-page":"405","article-title":"Clinical features in severe opisthorchiasis viverrini","volume":"16","author":"Pungpak","year":"1985","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000075107_ref008","first-page":"326","article-title":"An ether sedimentation technique for routine stool examinations","volume":"8","author":"Ritchie","year":"1984","journal-title":"Bulletin of the United States Army Medical Department"},{"key":"S0031182000075107_ref002","first-page":"413","article-title":"Studies on the chemotherapy of human opisthorchiasis. III. Minimum effective dose of Praziquantel","volume":"12","author":"Bunnag","year":"1981","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000075107_ref001","first-page":"528","article-title":"Studies on the chemotherapy of human opisthorchiasis in Thailand. I. Clinical trial of Praziquantel","volume":"11","author":"Bunnag","year":"1980","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0031182000075107_ref006","first-page":"1119","article-title":"Public health aspects of Opisthorchiasis in Thailand","volume":"34","author":"Preuksaraj","year":"1984","journal-title":"Arzneimittel Forschung\/Drug Research"},{"key":"S0031182000075107_ref004","first-page":"1164","article-title":"Opisthorchis viverrini: life-cycle, intermediate hosts, transmission to man and geographical distribution in Thailand","volume":"34","author":"Harinasuta","year":"1984","journal-title":"Arzneimittel Forschung\/Drug Research"},{"key":"S0031182000075107_ref009","first-page":"81","article-title":"Studies on Opisthorchis viverrini in Thailand","volume":"62","author":"Sadun","year":"1955","journal-title":"American Journal of Hygiene"},{"key":"S0031182000075107_ref005","first-page":"1164","article-title":"Opisthorchis viverrni: pathogenesis and clinical features","volume":"34","author":"Harinasuta","year":"1984","journal-title":"Arzneimittel Forschung \/Drug Research"},{"key":"S0031182000075107_ref010","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1984.11811877"},{"key":"S0031182000075107_ref011","first-page":"1231","article-title":"A pilot project for controlling O. viverrini infection in Nong Wai, Northeast Thailand, by applying praziquantel and other measures","volume":"34","author":"Sornmani","year":"1984","journal-title":"Arzneimittel Forschung\/Drug Research"},{"key":"S0031182000075107_ref012","first-page":"59","article-title":"Investigations on the control of hookworm disease. XV. An effective method of counting hookworm eggs in feces","volume":"3","author":"Stoll","year":"1923","journal-title":"American Journal of Hygiene"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000075107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T19:28:10Z","timestamp":1557948490000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000075107\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1993,4]]}},"alternative-id":["S0031182000075107"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000075107","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4]]}}}