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This model includes the explicit representation of changing worm distributions between hosts as a result of treatment, and estimates the morbidity due to heavy infections. The model is used to evaluate the effectiveness of different programmes of age-targeted community chemotherapy in reducing the amount of morbidity due to helminth infection. The magnitude of age-related heterogeneities is found to be very important in determining the results of age-targeted treatment programmes. The model was verified using field data from control programmes for<jats:italic>Ascaris lumbricoides<\/jats:italic>and<jats:italic>Trichuris trichiura<\/jats:italic>, and was found to provide accurate predictions of prevalence and mean intensities of infection during and following different control regimes.<\/jats:p>","DOI":"10.1017\/s0031182000078422","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T13:53:28Z","timestamp":1244210008000},"page":"389-396","source":"Crossref","is-referenced-by-count":49,"title":["The development and validation of an age-structured model for the evaluation of disease control strategies for intestinal helminths"],"prefix":"10.1017","volume":"109","author":[{"given":"M. S.","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. L.","family":"Guyatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. A. 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