{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:47:41Z","timestamp":1761155261681},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":13702,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1971,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>1 Populations of <jats:italic>Babesia rodhaini<\/jats:italic> were isolated which were \u2018putative\u2019 variants of a reference population.<\/jats:p><jats:p>2. They were shown to have some antigenic dissimilarity to the reference population by comparing the response of rats immunized with irradiated parasites of the reference population, to challenge with either the reference population or with the variant populations. To the homologous challenge the immunized rats were strongly resistant. After a heterologous challenge, however, for the first 3 or 4 days the immunized rats showed no resistance but thereafter rapidly controlled the infection.<\/jats:p><jats:p>3. Five \u2018variation\u2019 populations were tested and all were shown to have some antigenic dissimilarity to the reference population. Two variant populations were compared and were not found to be identical with each other. There appeared, however, to be less dissimilarity between them and any one variant and the reference population.<\/jats:p><jats:p>Mrs J. Page and her successor Miss D. Leader, gave technical assistance. I thank my colleagues for helpful criticism of the manuscript.<\/jats:p>","DOI":"10.1017\/s0031182000079622","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T17:07:16Z","timestamp":1244221636000},"page":"315-322","source":"Crossref","is-referenced-by-count":17,"title":["Antigenic variation in <i>Babesia rodhaini<\/i> demonstrated by immunization with irradiated parasites"],"prefix":"10.1017","volume":"63","author":[{"given":"R. S.","family":"Phillips","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000079622_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(69)90065-0"},{"key":"S0031182000079622_ref011","doi-asserted-by":"publisher","DOI":"10.1038\/2271255a0"},{"key":"S0031182000079622_ref010","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000082317"},{"key":"S0031182000079622_ref007","doi-asserted-by":"publisher","DOI":"10.1042\/bj0340442"},{"key":"S0031182000079622_ref006","doi-asserted-by":"publisher","DOI":"10.1038\/217267a0"},{"key":"S0031182000079622_ref004","unstructured":"Calver K. M. (1945). Chemotherapeutic studies on experimental Trypanosoma congolense infections. Ph.D. thesis University of Glasgow. Summarized in Tropical Diseases Bulletin 42, 704\u20139."},{"key":"S0031182000079622_ref003","doi-asserted-by":"publisher","DOI":"10.1038\/2081286a0"},{"key":"S0031182000079622_ref002","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0034-5288(18)34718-0","article-title":"The chemotherapy of Babesia bigemina infection in cattle","volume":"6","author":"Barnett","year":"1965","journal-title":"Research in Veterinary Science"},{"key":"S0031182000079622_ref001","first-page":"13","article-title":"Antigenic variation in Trypanosoma vivax of sheep","volume":"61","author":"Awan","year":"1967","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"S0031182000079622_ref009","doi-asserted-by":"publisher","DOI":"10.1038\/2051032a0"},{"key":"S0031182000079622_ref008","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1937.11684987"},{"key":"S0031182000079622_ref012","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000071468"},{"key":"S0031182000079622_ref005","first-page":"11","article-title":"Serological observations on relapsing fever in Madras","volume":"29","author":"Cunningham","year":"1925","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000079622","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T19:47:20Z","timestamp":1559332040000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000079622\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,10]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1971,10]]}},"alternative-id":["S0031182000079622"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000079622","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1971,10]]}}}