{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T03:04:56Z","timestamp":1712891096812},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":6823,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1990,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Sex ratios of adult schistosomes in mice are almost invariably different from 1\u00b70 and are biased towards males. The bias applies to wild rats infected with<jats:italic>Schistosoma japonicum<\/jats:italic>and trapped in an endemic area of the Philippines (male: female ratio = 1\u00b77). It also applies to cercariae of snails collected in such areas and assessed by infection of laboratory mice using cercariae from individual snails (male: female ratio may approach 6\u00b70). Experiments were designed to determine if duration of infection in the mammalian host was a factor that influenced the sex ratio of miracidia used for infecting snails and subsequently mice. BALB\/c and C57BL\/6 mice were infected with 100 cercariae of<jats:italic>S. mansoni<\/jats:italic>, and liver eggs harvested at early and late time points for infection of snails and production of cercariae. Two phenomena were demonstrated: firstly, a more pronounced male bias when eggs were harvested late compared with early in infection; secondly, a reduced apparent hatchability of eggs in BALB\/c compared with C57BL\/6 livers. The possibility is raised by the data that female miracidia within eggs of chronically infected individuals may be more prone to immune damage than male miracidia with important epidemiological consequences.<\/jats:p>","DOI":"10.1017\/s0031182000079713","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T14:39:37Z","timestamp":1244212777000},"page":"27-34","source":"Crossref","is-referenced-by-count":32,"title":["Studies on the sex ratio of worms in schistosome infections"],"prefix":"10.1017","volume":"101","author":[{"given":"G. F.","family":"Mitchell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. G.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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