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Test mice and sham-infected controls were autopsied 0, 4, 8, 10, 14 and 28 days post-primary infection (p-1\u00b0-i) and 2, 4, 5, 7 and 14 days post-secondary infection (p-2\u00b0-i), administered 28 days p-1\u00b0-i. Morphometric analysis revealed a statistically significant increase in crypt depth in the 60\u201370\u00b0<jats:sub>o<\/jats:sub>intestine region in infected mice during both primary and secondary infections; no significant deviation from the control was observed for villus height in infected mice. Statistical analysis showed a significant increase in the number of 5-HT-positive EC cells in infected mice. This response occurred in the lower portion of the intestine on days 10-p-1\u00b0-i and 5-p-2\u00b0-i, and was not due to increased mucosal surface area in this region. Results are discussed with reference to murine cestode rejection and the possible involvement therein of the neuroendocrine system.<\/jats:p>","DOI":"10.1017\/s0031182000079816","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T14:39:37Z","timestamp":1244212777000},"page":"107-113","source":"Crossref","is-referenced-by-count":23,"title":["<i>Hymenolepis diminuta<\/i>: changes in intestinal morphology and the enterochromaffin cell population associated with infection in male C57 mice"],"prefix":"10.1017","volume":"101","author":[{"given":"D. M.","family":"Mckay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. W.","family":"Halton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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