{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:15:11Z","timestamp":1761894911535},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":5119,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1995,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The relationship between varying intensities of<jats:italic>Trichuris trichiura<\/jats:italic>infection and iron status was examined in Jamaican schoolchildren, aged 7 to 11 years. A total of 409 children was identified with<jats:italic>T. trichiura<\/jats:italic>(epg &gt; 1200). A control group comprised 207 uninfected children who were matched by school and class to every pair of infected subjects. Blood samples were obtained from 421 children: 264 infected and 157 controls. Compared to the rest of the children, those with heavy infections (epg &gt; 10 000) had significantly lower (<jats:italic>P<\/jats:italic>&lt; 0\u00b705) Hb (11\u00b75 \u00b1 1\u00b73<jats:italic>vs<\/jats:italic>. 12\u00b71 \u00b1 1\u00b71 g\/dl), MCV (78\u00b76 \u00b1 6\u00b73<jats:italic>vs<\/jats:italic>. 81\u00b72 \u00b1 5\u00b75 fl), MCH (26\u00b72 \u00b1 2\u00b79<jats:italic>vs<\/jats:italic>. 27\u00b75 \u00b1 2\u00b75 pg) and MCHC (33\u00b72 \u00b1 1\u00b75<jats:italic>vs<\/jats:italic>. 33\u00b79 \u00b1 1\u00b74 g\/dl). Similarly, the prevalence of anaemia (Hb &lt; 11\u00b70 g\/dl) amongst heavily infected children (33%) was significantly higher (<jats:italic>P<\/jats:italic>&lt; 0\u00b705) than the rest of the sample (11%). These differences remained significant after controlling for confounding variables including socio-economic status, age, gender, area of residence and the presence of<jats:italic>Ascaris<\/jats:italic>infections. Differences in red cell count, ferritin, and free erythrocyte protoporphyrin were not statistically significant and showed no association with the infectious load. These results suggest that in the Jamaican children studied, iron deficiency anaemia is associated with<jats:italic>Trichuris<\/jats:italic>infections over 10 000 epg, but not with less intense infections.<\/jats:p>","DOI":"10.1017\/s0031182000080938","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T13:49:38Z","timestamp":1244209778000},"page":"347-351","source":"Crossref","is-referenced-by-count":49,"title":["Iron status of schoolchildren with varying intensities of<i>Trichuris trichiura<\/i>infection"],"prefix":"10.1017","volume":"110","author":[{"given":"D. D.","family":"Ramdath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. T.","family":"Simeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. S.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"Grantham-McGregor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000080938_ref021","doi-asserted-by":"publisher","DOI":"10.3109\/10408367909147133"},{"key":"S0031182000080938_ref020","doi-asserted-by":"publisher","DOI":"10.1079\/NRR19900004"},{"key":"S0031182000080938_ref018","first-page":"136","article-title":"Parasitic infections in young Jamaicans in different ecological zones of the island","volume":"43","author":"Rawlins","year":"1991","journal-title":"Tropical and Geographical Medicine"},{"key":"S0031182000080938_ref016","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1542\/peds.57.1.136","article-title":"Rapid diagnosis of iron deficiency by measurement of free erythrocyte porphyrins and hemoglobin: the FEP\/hemoglobin ratio","volume":"57","author":"Poimelli","year":"1976","journal-title":"Paediatrics"},{"key":"S0031182000080938_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90052-Z"},{"key":"S0031182000080938_ref013","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.73.9.1042"},{"key":"S0031182000080938_ref011","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1979.28.770"},{"key":"S0031182000080938_ref010","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/28.6.563"},{"key":"S0031182000080938_ref009","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/33.1.86"},{"key":"S0031182000080938_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000075272"},{"key":"S0031182000080938_ref006","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/47.3.496"},{"key":"S0031182000080938_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000055463"},{"key":"S0031182000080938_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(86)90369-X"},{"key":"S0031182000080938_ref002","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/42.6.1318"},{"key":"S0031182000080938_ref017","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/50.3.565"},{"key":"S0031182000080938_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90054-3"},{"key":"S0031182000080938_ref012","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1968.17.382"},{"key":"S0031182000080938_ref007","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1182\/blood.V48.3.449.449","article-title":"Evaluation of the iron status of a population","volume":"48","author":"Cook","year":"1976","journal-title":"Blood"},{"key":"S0031182000080938_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80703-3"},{"key":"S0031182000080938_ref015","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1935.s1-15.693"},{"key":"S0031182000080938_ref019","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(92)90176-D"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000080938","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T08:59:11Z","timestamp":1710406751000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000080938\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,4]]}},"alternative-id":["S0031182000080938"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000080938","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,4]]}}}