{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T06:57:51Z","timestamp":1698649071084},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"unspecified","delay-in-days":4966,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1995,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Much of what is currently known of the host-parasite interaction between mice and the parasitic nematode <jats:italic>Trichuris muris<\/jats:italic> has come from experiments using a single parasite isolate (E\/N). This isolate has been compared with 2 others which, on morphological criteria, belong to the same species. In 3 inbred strains of mouse that show distinct, genetically determined response phenotypes, there was a consistent pattern in terms of parasite survival time regardless of host strain, E\/K worms being expelled early, E\/N expelled later and S worms very late or not at all. High-responder CBA mice expelled E\/K and E\/N worms earlier than low-responder C57 B1\/10 mice. B10.BR mice were permissive to S isolate infection, mounted a very late response to E\/N worms but expelled E\/K worms effectively by day 25. The differential response of mice to these isolates provides an experimental system for identifying the basis of variation in this host-parasite relationship.<\/jats:p>","DOI":"10.1017\/s0031182000081907","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T13:45:09Z","timestamp":1244209509000},"page":"353-357","source":"Crossref","is-referenced-by-count":25,"title":["Isolates of <i>Trichuris muris<\/i> vary in their ability to elicit protective immune responses to infection in mice"],"prefix":"10.1017","volume":"111","author":[{"given":"T.","family":"Bellaby","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Wakelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Behnke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,4,6]]},"reference":[{"key":"S0031182000081907_ref003","first-page":"232","article-title":"Cellular immune responses to the murine nematode parasite Trichuris muris. II. Differential induction of TH-cell subsets in resistant versus susceptible mice","volume":"75","author":"Else","year":"1992","journal-title":"Immunology"},{"key":"S0031182000081907_ref002","first-page":"508","article-title":"Cellular immune responses to the murine nematode parasite Trichuris muris. I. Differential cytokine production during acute or chronic infection","volume":"72","author":"Else","year":"1991","journal-title":"Immunology"},{"key":"S0031182000081907_ref010","volume-title":"Trichocephalidae and Capillariidae of Animals and Man and the Diseases Caused by Them","author":"Skrjabin","year":"1957"},{"key":"S0031182000081907_ref008","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0020-7519(91)90121-M","article-title":"The absence of resistance in congenitally athymic nude mice towards infection with the intestinal nematode, Trichuris muris: resistance restored by lymphoid cell transfer","volume":"21","author":"Ito","year":"1991","journal-title":"International Journal for Parasitology"},{"key":"S0031182000081907_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000080173"},{"key":"S0031182000081907_ref007","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1938.s1-18.169"},{"key":"S0031182000081907_ref001","doi-asserted-by":"publisher","DOI":"10.1111\/pim.1993.15.10.595"},{"key":"S0031182000081907_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000062193"},{"key":"S0031182000081907_ref006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1990.tb00985.x"},{"key":"S0031182000081907_ref009","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"S0031182000081907_ref011","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000072395"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000081907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T20:55:23Z","timestamp":1557780923000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000081907\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["S0031182000081907"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000081907","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}