{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:10:21Z","timestamp":1784074221411,"version":"3.55.0"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2011,11,8]],"date-time":"2011-11-08T00:00:00Z","timestamp":1320710400000},"content-version":"unspecified","delay-in-days":10995,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1981,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A method using light and electron microscopes is described which is suitable for the examination of gut penetration by juvenile <jats:italic>Fasciola hepatica<\/jats:italic>. It involved the ligation of small sections of the small intestine of rats and the introduction of artificially excysted flukes into these gut loops. By restricting the area of infection in this way it was possible to either recover flukes from the gut lumen or to prepare ultrathin sections for electron microscopy of flukes penetrating the gut wall. In addition, flukes were recovered from the body cavity at various times after preparation of loops in resistant and naive rats. It was found that more flukes reached the body cavity in naive rats than in resistant rats, demonstrating a resistance to infection in the gut loops of sensitized rats.<\/jats:p>","DOI":"10.1017\/s0031182000085255","type":"journal-article","created":{"date-parts":[[2011,11,8]],"date-time":"2011-11-08T14:46:15Z","timestamp":1320763575000},"page":"249-252","source":"Crossref","is-referenced-by-count":7,"title":["<i>Fasciola hepatica<\/i>: a technique for the study of gut penetration by juvenile flukes"],"prefix":"10.1017","volume":"83","author":[{"given":"D. J.","family":"Burden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. P.","family":"Bland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. L.","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. C.","family":"Hammet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2011,11,8]]},"reference":[{"key":"S0031182000085255_ref001","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000072589"},{"key":"S0031182000085255_ref004","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0034-5288(18)33819-0","article-title":"The recovery after oral infection of immature Fasciola hepatica from the peritoneal cavity of two strains of mice","volume":"15","author":"Harness","year":"1973","journal-title":"Research in Veterinary Science"},{"key":"S0031182000085255_ref007","first-page":"755","article-title":"Immunity to Fasciola hepatica infection in albino rats vaccinated with irradiated metacercariae","volume":"74","author":"Thorpe","year":"1962","journal-title":"Veterinary Record"},{"key":"S0031182000085255_ref006","first-page":"4","article-title":"Fasciola hepatica: the stimulation of excystation","volume":"59","author":"Sewell","year":"1969","journal-title":"Parasitology"},{"key":"S0031182000085255_ref005","unstructured":"Hughes D. L. (1959). Chemotherapy of experimental Fasciola hepaiica infection. M.Sc. thesis, University of London."},{"key":"S0031182000085255_ref003","first-page":"xxv","article-title":"Naturally acquired immunity to Fasciola hepatica in the rat","volume":"67","author":"Goose","year":"1973","journal-title":"Parasitology"},{"key":"S0031182000085255_ref002","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0034-5288(18)33006-6","article-title":"Resistance of the rat to reinfection with Fasciola hepatica and the possible involvement of intestinal eosinophil leucocytes","volume":"25","author":"Doy","year":"1978","journal-title":"Research in Veterinary Science"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182000085255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T19:30:45Z","timestamp":1558812645000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182000085255\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,10]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1981,10]]}},"alternative-id":["S0031182000085255"],"URL":"https:\/\/doi.org\/10.1017\/s0031182000085255","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,10]]}}}