{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T14:20:25Z","timestamp":1725373225959},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2001,8,7]],"date-time":"2001-08-07T00:00:00Z","timestamp":997142400000},"content-version":"unspecified","delay-in-days":98,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:p>The objective of this experiment was to detect a possible interaction between iron deficiency and intestinal nematode infections. We report on a 2\u00d72 study where thirty-one 10-week-old pigs fed a low or a normal iron diet were infected with both<jats:italic>Trichuris suis<\/jats:italic>(4500 eggs) and<jats:italic>Ascaris suum<\/jats:italic>(1200 eggs). No significant difference was detected between diet groups with respect to parasitological parameters for<jats:italic>A. suum<\/jats:italic>or the total number of adult<jats:italic>T. suis<\/jats:italic>recovered at necropsy 10 weeks p.i. However, in the low iron group<jats:italic>T. suis<\/jats:italic>were located more proximally and the worms were increased in length. A higher proportion of pigs with initial faecal egg excretion at 6 weeks p.i. was observed in the low iron group, indicating a shortened pre-patency period. Worm fecundity and total faecal egg excretion were also highest in the low iron group. A significant correlation was found between female worm length and fecundity. The peripheral eosinophil counts were diminished in the low iron host groups. The infected low iron group experienced more severe pathophysiological changes in terms of hypoalbuminaemia and decreases in erythrocyte volumes. A significant inverse correlation existed between iron content in the bone-marrow and liver (body) store. In conclusion, iron deficiency increased the severity of<jats:italic>T. suis<\/jats:italic>infection in pigs.<\/jats:p>","DOI":"10.1017\/s0031182001007582","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:16:36Z","timestamp":1027775796000},"page":"589-598","source":"Crossref","is-referenced-by-count":22,"title":["Effect of iron deficiency on<i>Trichuris suis<\/i>and<i>Ascaris suum<\/i>infections in pigs"],"prefix":"10.1017","volume":"122","author":[{"given":"S.","family":"PEDERSEN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"SAEED","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"FRIIS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. F.","family":"MICHAELSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2001,8,7]]},"reference":[{"key":"S0031182001007582_ref005","doi-asserted-by":"crossref","unstructured":"BEER, R. J. S. & LEAN, I. J. (1973). Clinical trichuriasis produced experimentally in growing pigs. Part 1: Pathology of infection. Veterinary Record 93, 189\u2013195.","DOI":"10.1136\/vr.93.7.189"},{"key":"S0031182001007582_ref004","doi-asserted-by":"crossref","unstructured":"BEER, R. J. S. (1973b). Morphological descriptions of the egg and larval stages of Trichuris suis Schrank, 1788. Parasitology 67, 263\u2013278.","DOI":"10.1017\/S0031182000046503"},{"key":"S0031182001007582_ref020","doi-asserted-by":"crossref","unstructured":"MILLER, R. A. & BRITIGAN, B. E. (1997). Role of oxidants in microbial pathophysiology. Clinical Microbiology Reviews 10, 1\u201318.","DOI":"10.1128\/CMR.10.1.1"},{"key":"S0031182001007582_ref030","unstructured":"WORLD HEALTH ORGANIZATION . (1998). Life in the 21st Century: A Vision for All. Report of the Director General of the World Health Organization. WHO, Geneva, Switzerland."},{"key":"S0031182001007582_ref028","unstructured":"STOLTZFUS, R. & DREYFUSS, M. (1998). Guidelines for the Use of Iron Supplements to Prevent and Treat Iron Deficiency Anaemia. The International Nutritional Anaemia Consultative group (INACG\/WHO\/UNICEF), Washington, DC, USA."},{"key":"S0031182001007582_ref003","doi-asserted-by":"crossref","unstructured":"BEER, R. J. S. (1973a). Studies on the biology of the life-cycle of Trichuris suis Schrank, 1788. Parasitology 67, 253\u2013262.","DOI":"10.1017\/S0031182000046497"},{"key":"S0031182001007582_ref001","unstructured":"ALLEN, L. & AHLUWALIA, N. (1997). Improving Iron Status Through Diets: The Application of Knowledge Correcting Dietary Iron Bioavailability in Human Populations . OMNI\/USAID, Arlington, VA, USA."},{"key":"S0031182001007582_ref007","doi-asserted-by":"publisher","DOI":"10.1136\/vr.88.17.436"},{"key":"S0031182001007582_ref018","unstructured":"HOLLAND, C. (1987). Neglected infections\u2013trichuriasis and strongyloidiasis. In Impact of Helminth Infections on Human Nutrition (ed. STEPHENSON, L. S .), pp. 161\u2013201. Taylor & Francis; London."},{"key":"S0031182001007582_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(76)90090-X"},{"key":"S0031182001007582_ref002","unstructured":"BATTE, E. G. , MCLAMB, R. D. , MUSE, K. E. , TALLY, S. D. & VESTAL, T. J. (1977). Pathophysiology of swine trichuriasis. American Journal of Veterinary Research 38, 1075\u20131079."},{"key":"S0031182001007582_ref008","doi-asserted-by":"publisher","DOI":"10.1093\/4.4.746"},{"key":"S0031182001007582_ref027","unstructured":"STEPHENSON, L. S. (1987). Impact of Helminth Infections on Human Nutrition . Taylor & Francis, London."},{"key":"S0031182001007582_ref017","doi-asserted-by":"crossref","unstructured":"FLEMING, A. (1982). Iron deficiency in the tropics. Clinics in Haematology 11, 365\u2013388.","DOI":"10.1016\/S0308-2261(21)00343-X"},{"key":"S0031182001007582_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(99)00070-9"},{"key":"S0031182001007582_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(74)90007-3"},{"key":"S0031182001007582_ref015","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/46.2.329"},{"key":"S0031182001007582_ref016","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/32.3.553"},{"key":"S0031182001007582_ref013","unstructured":"CHWALIBOG, A. (1997). Husdyrern\u0153ring. Bestemmelse af N\u0153ringsv\u0153rdi og N\u0153ringsbehov, 3. udgave. DSR forlag, K\u00f8benhavn (in Danish)."},{"key":"S0031182001007582_ref023","unstructured":"POWERS, K. G. , TODD, A. C. & MCNUTT, S. H. (1960). Experimental infections of swine with Trichuris suis . American Journal of Veterinary Research 21, 262\u2013268."},{"key":"S0031182001007582_ref024","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(97)00022-2"},{"key":"S0031182001007582_ref025","unstructured":"ROEPSTORFF, A. & NANSEN, P. (1998). The Epidemiology, Diagnosis and Control of Helminth Parasites of Swine. FAO Animal Health Manual, No. 3. 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